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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL417171
Molecular formula	C21H26F3NO4
IUPAC name	7-[(2R)-2-[(E)-3-hydroxy-3-[3-(trifluoromethyl)phenyl]prop-1-enyl]-5-oxopyrrolidin-1-yl]heptanoic acid
Molecular weight	413.437
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	3.1
Synonyms	BDBM50142479 SCHEMBL5733260 7-{(R)-2-[(E)-3-Hydroxy-3-(3-trifluoromethyl-phenyl)-propenyl]-5-oxo-pyrrolidin-1-yl}-heptanoic acid
Inchi Key	ALOFPCCPHHKNFS-UFNCHRQHSA-N
Inchi ID	InChI=1S/C21H26F3NO4/c22-21(23,24)16-7-5-6-15(14-16)18(26)11-9-17-10-12-19(27)25(17)13-4-2-1-3-8-20(28)29/h5-7,9,11,14,17-18,26H,1-4,8,10,12-13H2,(H,28,29)/b11-9+/t17-,18?/m0/s1
PubChem CID	44289977
ChEMBL	CHEMBL417171
IUPHAR	N/A
BindingDB	50142479
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
8448	Prostaglandin E2 receptor EP2 subtype	P43116	PTGER2	Homo sapiens (Human)	358
8447	Prostaglandin E2 receptor EP3 subtype	P43115	PTGER3	Homo sapiens (Human)	390
8446	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488

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