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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL346711
Molecular formula	C31H37ClFN5O4
IUPAC name	4-chloro-N-[(2R)-1-[4-[3-[4-[5-(cyclopentylmethyl)-1,2,4-oxadiazol-3-yl]-3-fluorophenoxy]propyl]piperazin-1-yl]-1-oxopropan-2-yl]benzamide
Molecular weight	598.116
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	6.1
Synonyms	BDBM50139317 2-(4-Chloro-phenyl)-N-[(R)-2-(4-{3-[4-(5-cyclopentylmethyl-[1,2,4]oxadiazol-3-yl)-3-fluoro-phenoxy]-propyl}-piperazin-1-yl)-1-methyl-2-oxo-ethyl]-acetamide
Inchi Key	ALNCEGZMYYLYMF-OAQYLSRUSA-N
Inchi ID	InChI=1S/C31H37ClFN5O4/c1-21(34-30(39)23-7-9-24(32)10-8-23)31(40)38-16-14-37(15-17-38)13-4-18-41-25-11-12-26(27(33)20-25)29-35-28(42-36-29)19-22-5-2-3-6-22/h7-12,20-22H,2-6,13-19H2,1H3,(H,34,39)/t21-/m1/s1
PubChem CID	44374106
ChEMBL	CHEMBL346711
IUPHAR	N/A
BindingDB	50139317
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
8418	Histamine H3 receptor	Q9QYN8	Hrh3	Rattus norvegicus (Rat)	445
8419	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445

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