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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL431523
Molecular formula	C24H31N5O2
IUPAC name	(2S)-N-(4-aminobutyl)-3-(1H-indol-3-yl)-2-(2-phenylethylcarbamoylamino)propanamide
Molecular weight	421.545
Hydrogen bond acceptor	3
Hydrogen bond donor	5
XlogP	1.7
Synonyms	BDBM50129192 N-(4-Amino-butyl)-3-(1H-indol-3-yl)-2-(3-phenethyl-ureido)-propionamide
Inchi Key	ALCIJSWNWVGYMD-QFIPXVFZSA-N
Inchi ID	InChI=1S/C24H31N5O2/c25-13-6-7-14-26-23(30)22(16-19-17-28-21-11-5-4-10-20(19)21)29-24(31)27-15-12-18-8-2-1-3-9-18/h1-5,8-11,17,22,28H,6-7,12-16,25H2,(H,26,30)(H2,27,29,31)/t22-/m0/s1
PubChem CID	44305753
ChEMBL	CHEMBL431523
IUPHAR	N/A
BindingDB	50129192
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
8132	Melanocortin receptor 3	P33033	Mc3r	Mus musculus (Mouse)	323
8133	Melanocortin receptor 4	P56450	Mc4r	Mus musculus (Mouse)	332
8135	Melanocortin receptor 5	P41149	Mc5r	Mus musculus (Mouse)	325
8134	Melanocyte-stimulating hormone receptor	Q01727	Mc1r	Mus musculus (Mouse)	315

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