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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL208685
Molecular formula	C21H22F6N2OS
IUPAC name	(2S)-N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-[2-(dimethylamino)ethylsulfanyl]-2-phenylacetamide
Molecular weight	464.47
Hydrogen bond acceptor	9
Hydrogen bond donor	1
XlogP	5.2
Synonyms	BDBM50187047 (S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-(dimethylamino)ethylthio)-2-phenylacetamide
Inchi Key	ALCHXFSAGPIQMB-SFHVURJKSA-N
Inchi ID	InChI=1S/C21H22F6N2OS/c1-29(2)8-9-31-18(15-6-4-3-5-7-15)19(30)28-13-14-10-16(20(22,23)24)12-17(11-14)21(25,26)27/h3-7,10-12,18H,8-9,13H2,1-2H3,(H,28,30)/t18-/m0/s1
PubChem CID	44413257
ChEMBL	CHEMBL208685
IUPHAR	N/A
BindingDB	50187047
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
8131	C-C chemokine receptor type 2	P41597	CCR2	Homo sapiens (Human)	374

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