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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL80711
Molecular formula	C22H28N4O2
IUPAC name	N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-4H-1,4-benzoxazin-3-imine
Molecular weight	380.492
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.9
Synonyms	(2H-Benzo[1,4]oxazin-3-yl)-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-amine; compound with but-2-enedioic acid CHEMBL1179506 BDBM50290197
Inchi Key	AKTQSTPCOLTVQO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H28N4O2/c1-27-21-10-5-3-8-19(21)26-15-13-25(14-16-26)12-6-11-23-22-17-28-20-9-4-2-7-18(20)24-22/h2-5,7-10H,6,11-17H2,1H3,(H,23,24)
PubChem CID	135887940
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50290197
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
7890	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
7891	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
7892	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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