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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Tavapadon
Molecular formula	C19H16F3N3O3
IUPAC name	1,5-dimethyl-6-[2-methyl-4-[3-(trifluoromethyl)pyridin-2-yl]oxyphenyl]pyrimidine-2,4-dione
Molecular weight	391.35
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	3.3
Synonyms	CHEMBL3697617 SCHEMBL16334991 (-)-1,5-dimethyl-6-(2-methyl-4-((3-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-2,4(1H,3H)-pyrimidinedione UNII-PT4P8MJP8L 2,4(1H,3H)-Pyrimidinedione, 1,5-dimethyl-6-(2-methyl-4-((3-(trifluoromethyl)-2-pyridinyl)oxy)phenyl)-, (-)- PF-06649751 PT4P8MJP8L Tavapadon [USAN] 1643489-24-0 [ Show all ]
Inchi Key	AKQXQLUNFKDZBN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H16F3N3O3/c1-10-9-12(28-17-14(19(20,21)22)5-4-8-23-17)6-7-13(10)15-11(2)16(26)24-18(27)25(15)3/h4-9H,1-3H3,(H,24,26,27)
PubChem CID	86764100
ChEMBL	CHEMBL3697617
IUPHAR	N/A
BindingDB	160918
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
459286	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446

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