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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1682628
Molecular formula	C33H37Cl2N3O2
IUPAC name	2-[(4-acetamido-4-phenylpiperidin-1-yl)methyl]-1-(3,4-dichlorophenyl)-N-methyl-N-[(2-methylphenyl)methyl]cyclopropane-1-carboxamide
Molecular weight	578.578
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	5.9
Synonyms	BDBM50337425 rac-2-((4-acetamido-4-phenylpiperidin-1-yl)methyl)-1-(3,4-dichlorophenyl)-N-methyl-N-(2-methylbenzyl)cyclopropanecarboxamide
Inchi Key	AKNNBMGJZOFXCC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C33H37Cl2N3O2/c1-23-9-7-8-10-25(23)21-37(3)31(40)33(27-13-14-29(34)30(35)19-27)20-28(33)22-38-17-15-32(16-18-38,36-24(2)39)26-11-5-4-6-12-26/h4-14,19,28H,15-18,20-22H2,1-3H3,(H,36,39)
PubChem CID	53317081
ChEMBL	CHEMBL1682628
IUPHAR	N/A
BindingDB	50337425
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
7718	Neuromedin-K receptor	P29371	TACR3	Homo sapiens (Human)	465

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