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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL388520
Molecular formula	C22H21FN6
IUPAC name	N-cyclopentyl-3-[(2-fluorophenyl)methyl]-5-phenyltriazolo[4,5-d]pyrimidin-7-amine
Molecular weight	388.45
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	4.7
Synonyms	BDBM50196003 3-(2-fluorobenzyl)-N-cyclopentyl-5-phenyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-amine
Inchi Key	AKMVZWIYTSGYAG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H21FN6/c23-18-13-7-4-10-16(18)14-29-22-19(27-28-29)21(24-17-11-5-6-12-17)25-20(26-22)15-8-2-1-3-9-15/h1-4,7-10,13,17H,5-6,11-12,14H2,(H,24,25,26)
PubChem CID	16111766
ChEMBL	CHEMBL388520
IUPHAR	N/A
BindingDB	50196003
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
7703	Adenosine receptor A1	P28190	ADORA1	Bos taurus (Bovine)	326
7702	Adenosine receptor A2a	P29274	ADORA2A	Homo sapiens (Human)	412
442017	Adenosine receptor A3	P0DMS8	ADORA3	Homo sapiens (Human)	318

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