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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	1-[(2-chlorophenyl)sulfanyl]-3-[4-(2-fluorophenyl)piperazino]-2-propanol
Molecular formula	C19H22ClFN2OS
IUPAC name	1-(2-chlorophenyl)sulfanyl-3-[4-(2-fluorophenyl)piperazin-1-yl]propan-2-ol
Molecular weight	380.906
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.2
Synonyms	1-(2-chlorophenyl)sulfanyl-3-[4-(2-fluorophenyl)piperazin-1-yl]propan-2-ol Oprea1_836360 338421-90-2 HMS573G14 AKOS005091196 MLS000325625 1-[(2-chlorophenyl)sulfanyl]-3-[4-(2-fluorophenyl)piperazin-1-yl]propan-2-ol CHEMBL1320396 SMR000169950 4H-463S KS-000037EG Bionet1_001812 MolPort-002-868-036 HMS2460L04 AC1NCQ95 MCULE-5698514989 [ Show all ]
Inchi Key	AJYMPTJHOJJOAX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H22ClFN2OS/c20-16-5-1-4-8-19(16)25-14-15(24)13-22-9-11-23(12-10-22)18-7-3-2-6-17(18)21/h1-8,15,24H,9-14H2
PubChem CID	4562984
ChEMBL	CHEMBL1320396
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
463788	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
463789	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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