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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL303743
Molecular formula	C21H22ClN3O6S2
IUPAC name	[3-[[3-[(4-chloro-3-methyl-1,2-oxazol-5-yl)sulfamoyl]thiophene-2-carbonyl]amino]-2,4,6-trimethylphenyl]methyl acetate
Molecular weight	511.992
Hydrogen bond acceptor	9
Hydrogen bond donor	2
XlogP	3.9
Synonyms	N-(4-chloro-3-methyl-5-isoxazolyl)-2-(3-acetoxymethyl-2,4,6-trimethylphenylaminocarbonyl)thiophene-3-sulfonamide 2-[[[3-(Acetoxymethyl)-2,4,6-trimethylphenyl]amino]carbonyl]-N-(4-chloro-3-methylisoxazole-5-yl)-3-thiophenesulfonamide SCHEMBL4631362 AJDYXXCWHDGBML-UHFFFAOYSA-N N-(4-chloro-3-methyl-5-isoxazolyl)-2-(3-acetoxymethyl-2,4, 6-trimethylphenylaminocarbonyl)thiophene-3-sulfonamide
Inchi Key	AJDYXXCWHDGBML-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H22ClN3O6S2/c1-10-8-11(2)18(12(3)15(10)9-30-14(5)26)23-20(27)19-16(6-7-32-19)33(28,29)25-21-17(22)13(4)24-31-21/h6-8,25H,9H2,1-5H3,(H,23,27)
PubChem CID	10791859
ChEMBL	CHEMBL303743
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
6824	Endothelin-1 receptor	P25101	EDNRA	Homo sapiens (Human)	427

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