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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL99198
Molecular formula	C30H34N2O2
IUPAC name	N-[4-[(4aS,10bS)-7-hydroxy-2,3,4a,5,6,10b-hexahydro-1H-benzo[f]quinolin-4-yl]butyl]-4-phenylbenzamide
Molecular weight	454.614
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	5.9
Synonyms	AIXVGZUOFPCOMV-XCZPVHLTSA-N Biphenyl-4-carboxylic acid [4-(7-hydroxy-2,3,4a,5,6,10b-hexahydro-1H-benzo[f]quinolin-4-yl)-butyl]-amide SCHEMBL8161814 BDBM50132022 trans-7-hydroxy-4-(4-(4-phenylbenzoylamino)butyl)-1,2,3,4,4a,5,6,10b-octahydrobenzo[f]quinoline Biphenyl-4-carboxylic acid [4-((4aS,10bS)-7-hydroxy-2,3,4a,5,6,10b-hexahydro-1H-benzo[f]quinolin-4-yl)-butyl]-amide [ Show all ]
Inchi Key	AIXVGZUOFPCOMV-XCZPVHLTSA-N
Inchi ID	InChI=1S/C30H34N2O2/c33-29-12-6-10-25-26-11-7-21-32(28(26)18-17-27(25)29)20-5-4-19-31-30(34)24-15-13-23(14-16-24)22-8-2-1-3-9-22/h1-3,6,8-10,12-16,26,28,33H,4-5,7,11,17-21H2,(H,31,34)/t26-,28-/m0/s1
PubChem CID	44329321
ChEMBL	CHEMBL99198
IUPHAR	N/A
BindingDB	50132022
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
6640	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
6639	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400

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