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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL481614
Molecular formula	C25H22Cl2F2N2O4S
IUPAC name	(E)-N-(3,5-dichlorophenyl)sulfonyl-3-[1-[(3,4-difluorophenyl)methyl]-3a-methyl-2-oxo-3,4,5,6-tetrahydroindol-7-yl]prop-2-enamide
Molecular weight	555.418
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	4.7
Synonyms	BDBM50255286 N-(3,5-dichlorophenylsulfonyl)-3-(1-(3,4-difluorobenzyl)-3a-methyl-2-oxo-2,3,3a,4,5,6-hexahydro-1H-indol-7-yl)acrylamide
Inchi Key	AIEHEPFQGINRGI-FNORWQNLSA-N
Inchi ID	InChI=1S/C25H22Cl2F2N2O4S/c1-25-8-2-3-16(5-7-22(32)30-36(34,35)19-11-17(26)10-18(27)12-19)24(25)31(23(33)13-25)14-15-4-6-20(28)21(29)9-15/h4-7,9-12H,2-3,8,13-14H2,1H3,(H,30,32)/b7-5+
PubChem CID	44570829
ChEMBL	CHEMBL481614
IUPHAR	N/A
BindingDB	50255286
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
6135	Prostaglandin E2 receptor EP3 subtype	P43115	PTGER3	Homo sapiens (Human)	390

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