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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL181251
Molecular formula	C23H23BrF3N5O2
IUPAC name	[4-bromo-2-(trifluoromethoxy)phenyl]-[4-[[4-(dimethylamino)quinazolin-2-yl]amino]piperidin-1-yl]methanone
Molecular weight	538.369
Hydrogen bond acceptor	9
Hydrogen bond donor	1
XlogP	5.9
Synonyms	BDBM50170188 SCHEMBL13793628 (4-Bromo-2-trifluoromethoxy-phenyl)-[4-(4-dimethylamino-quinazolin-2-ylamino)-piperidin-1-yl]-methanone
Inchi Key	AHAIAGUVLZQAPM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H23BrF3N5O2/c1-31(2)20-16-5-3-4-6-18(16)29-22(30-20)28-15-9-11-32(12-10-15)21(33)17-8-7-14(24)13-19(17)34-23(25,26)27/h3-8,13,15H,9-12H2,1-2H3,(H,28,29,30)
PubChem CID	44390748
ChEMBL	CHEMBL181251
IUPHAR	N/A
BindingDB	50170188
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
5388	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422

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