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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL299726
Molecular formula	C20H17ClN4O2
IUPAC name	6-chloro-N-[6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-2,3-dihydroindole-1-carboxamide
Molecular weight	380.832
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.5
Synonyms	N-[6-(2-Methyl-3-pyridinyloxy)-3-pyridinyl]-6-chloroindoline-1-carboxamide 6-Chloro-2,3-dihydro-indole-1-carboxylic acid [6-(2-methyl-pyridin-3-yloxy)-pyridin-3-yl]-amide 6-chloro-N-(6-(2-methylpyridin-3-yloxy)pyridin-3-yl)indoline-1-carboxamide BDBM50321891
Inchi Key	AGVPOFROVYICOD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H17ClN4O2/c1-13-18(3-2-9-22-13)27-19-7-6-16(12-23-19)24-20(26)25-10-8-14-4-5-15(21)11-17(14)25/h2-7,9,11-12H,8,10H2,1H3,(H,24,26)
PubChem CID	44298142
ChEMBL	CHEMBL299726
IUPHAR	N/A
BindingDB	50321891
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
5260	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
5262	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
5261	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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