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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000727578
Molecular formula	C23H21BrN4O
IUPAC name	6-bromo-N-[(1,3-dimethylpyrazol-4-yl)methyl]-N-methyl-2-phenylquinoline-4-carboxamide
Molecular weight	449.352
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	4.2
Synonyms	6-bromo-N-[(1,3-dimethyl-1H-pyrazol-4-yl)methyl]-N-methyl-2-phenylquinoline-4-carboxamide N-[(1,3-dimethylpyrazol-4-yl)methyl](6-bromo-2-phenyl(4-quinolyl))-N-methylcar boxamide ST50937796 6-bromo-N-[(1,3-dimethylpyrazol-4-yl)methyl]-N-methyl-2-phenylquinoline-4-carboxamide EU-0050146 AKOS001691941 6-bromo-N-[(1,3-dimethyl-4-pyrazolyl)methyl]-N-methyl-2-phenyl-4-quinolinecarboxamide CHEMBL1328648 NCGC00101023-01 STK422675 6-bromo-N~4~-[(1,3-dimethyl-1H-pyrazol-4-yl)methyl]-N~4~-methyl-2-phenyl-4-quinolinecarboxamide HMS1803O08 6-bromanyl-N-[(1,3-dimethylpyrazol-4-yl)methyl]-N-methyl-2-phenyl-quinoline-4-carboxamide BDBM114387 MolPort-001-535-134 6-bromo-N-[(1,3-dimethylpyrazol-4-yl)methyl]-N-methyl-2-phenyl-cinchoninamide cid_5048043 SMR000306275 ZINC2769037 AC1NNNDV MCULE-5602260781 [ Show all ]
Inchi Key	AGHSRUDOCZHHSV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H21BrN4O/c1-15-17(14-28(3)26-15)13-27(2)23(29)20-12-22(16-7-5-4-6-8-16)25-21-10-9-18(24)11-19(20)21/h4-12,14H,13H2,1-3H3
PubChem CID	5048043
ChEMBL	CHEMBL1328648
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
4883	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
4882	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371
4881	Relaxin receptor 1	Q9HBX9	RXFP1	Homo sapiens (Human)	757

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