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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1086514
Molecular formula	C27H27N3O
IUPAC name	1-[4-[6-[2-[(2R)-2-methylpyrrolidin-1-yl]ethyl]quinolin-2-yl]phenyl]pyridin-4-one
Molecular weight	409.533
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	5.0
Synonyms	1-(4-{6-[2-((2R)-2-Methyl-pyrrolidin-1-yl)-ethyl]-quinolin-2-yl}-phenyl)-1H-pyridin-4-one BDBM50319538 (R)-1-(4-(6-(2-(2-methylpyrrolidin-1-yl)ethyl)quinolin-2-yl)phenyl)pyridin-4(1H)-one SCHEMBL1575300 1-(4-[6-{2-((2R)-2-Methyl-pyrrolidin-1-yl)-ethyl]-quinolin-2-yl}-phenyl)-1H-pyridin-4-one AFPODXVEPNVDCE-HXUWFJFHSA-N [ Show all ]
Inchi Key	AFPODXVEPNVDCE-HXUWFJFHSA-N
Inchi ID	InChI=1S/C27H27N3O/c1-20-3-2-15-29(20)16-12-21-4-10-27-23(19-21)7-11-26(28-27)22-5-8-24(9-6-22)30-17-13-25(31)14-18-30/h4-11,13-14,17-20H,2-3,12,15-16H2,1H3/t20-/m1/s1
PubChem CID	11531634
ChEMBL	CHEMBL1086514
IUPHAR	N/A
BindingDB	50319538
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
4378	Histamine H3 receptor	Q9QYN8	Hrh3	Rattus norvegicus (Rat)	445
4379	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445

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