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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL418160
Molecular formula	C27H32ClFN4O
IUPAC name	1-[5-[4-[5-chloro-1-(4-fluorophenyl)indol-3-yl]piperidin-1-yl]pentyl]imidazolidin-2-one
Molecular weight	483.028
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	5.1
Synonyms	1-(5-{4-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-pentyl)-imidazolidin-2-one BDBM50002010 SCHEMBL7382323 5-Chloro-1-(4-fluorophenyl)-3-[1-[5-(2-oxo-1-imidazolidinyl)pentyl]-4-piperidinyl]-1H-indole
Inchi Key	AFKBRSCMNVQDCS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H32ClFN4O/c28-21-4-9-26-24(18-21)25(19-33(26)23-7-5-22(29)6-8-23)20-10-15-31(16-11-20)13-2-1-3-14-32-17-12-30-27(32)34/h4-9,18-20H,1-3,10-17H2,(H,30,34)
PubChem CID	15006462
ChEMBL	CHEMBL418160
IUPHAR	N/A
BindingDB	50002010
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
4231	D(2) dopamine receptor	P61168	Drd2	Mus musculus (Mouse)	444
4232	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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