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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	4-Methoxycinnamic acid
Molecular formula	C10H10O3
IUPAC name	(E)-3-(4-methoxyphenyl)prop-2-enoic acid
Molecular weight	178.187
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	1.8
Synonyms	AC1LF8QH PS-5777 AKOS A1230-2778 SC-77648 ART-CHEM-BB B000181 TR-029508 CAS-943-89-5 W-100196 DSSTox_GSID_46059 (2E)-3-(4-Methoxyphenyl)-2-propenoic acid # HMS2267B19 (E)-3-(4-methoxyphenyl)prop-2-enoic acid LS11390 3-(4-Methoxy-phenyl)-acrylate MP-2212 4-Methoxy cinnamic acid NSC623437 6G4ML8401A p-methoxy-cinnamic acid p-Methoxycinnamic acid, 99%, predominantly trans AFDXODALSZRGIH-QPJJXVBHSA- RP17443 AKOS BBS-00000769 ST098720 BBL012085 trans-3-(4-Methoxyphenyl)acrylic acid CHEMBL95770 EBD2197791 (E)-3-(4-Methoxy-phenyl)-acrylic acid InChI=1/C10H10O3/c1-13-9-5-2-8(3-6-9)4-7-10(11)12/h2-7H,1H3,(H,11,12)/b7-4+ (E)-p-Methoxycinnamic acid METHOXYCINNAMIC ACID, PARA 3-(4-Methoxyphenyl)-2-propenoic acid NCGC00159448-04 4-Methoxycinnamate O-Methyl-p-cumaric Acid 830M091 para-methoxycinnamic acid AJ-10423 SBB005717 AN-20523 TIMTEC-BB SBB005717 Bernel hydro trans-4-Methoxycinnamic acid CS-0016807 F1638-0067 (E)-3-(4-Methoxyphenyl)acrylate LABOTEST-BB LT03333631 2-Propenoic acid, 3-(4-methoxyphenyl)-, (2E)- MLS002473129 30-09-1 NSC-623437 4-Methoxycinnamic acid, predominantly trans P-Methoxy ciannamate AB1003581 AC1Q5RAR PubChem8248 AKOS B000181 SCHEMBL58699 AS01561 TR-049560 CHEBI:48541 W-104154 DSSTox_RID_81310 (2E)-3-(4-METHOXYPHENYL)ACRYLIC ACID HY-N1387 (E)-4-METHOXYCINNAMIC ACID M0576 3-(4-Methoxy-phenyl)-acrylic acid NCGC00159448-02 4-Methoxy-(2E)-cinnamic acid O-Methyl-p-coumarate 7340-42-3 (hydrochloride salt) p-methoxycinnamate p-Methoxycinnamic acid, predominantly trans AFDXODALSZRGIH-QPJJXVBHSA-N RTR-025896 AKOS000118882 ST2410363 BCP21420 trans-4-methoxy-cinnamic acid Cinnamic acid, 4-methoxy- EINECS 212-594-0 (E)-3-(4-methoxyphenyl)-2-propenoic acid KB-72675 0C546A89-9721-4B4E-89EE-7EC28A9A3391 METHOXYCINNAMIC ACID,4- 3-(4-methoxyphenyl)acrylic acid NSC 5303 OTAVA-BB 0123400502 943-89-5 AC-10371 PMCA AK-98686 SC-50019 ARONIS000351 Tox21_111674 bmse010212 UNII-6G4ML8401A DSSTox_CID_26059 HMS1783A08 (E)-3-(4-Methoxyphenyl)acrylic acid LS-123672 2-Propenoic acid, 3-(4-methoxyphenyl)-, (E)- MolPort-000-655-960 4-Methoxy cinnamate NSC5303 4-Methoxycinnamic acid, predominantly trans, 99% P-Methoxy ciannamic acid AE-641/00135031 RARECHEM BK HC T257 AKOS BBB/225 SMR000112200 AZ0001-0155 trans-2-Propenoic acid, 3-(4-methoxyphenyl)- ZINC77999 DTXSID1046059 (2E)-3-(4-methoxyphenyl)prop-2-enoic acid I04-9543 (E)-p-Methoxy-cinnamic acid MCULE-6993960877 3-(4-methoxyphenyl)-2-Propenoate NCGC00159448-03 4-Methoxybenzeneacrylic acid O-Methyl-p-coumaric acid 830-09-1 P-METHOXYCINNAMIC ACID para-methoxycinnamate AI3-23399 RTR-029508 ALBB-011726 STK005095 BDBM50146453 trans-4-Methoxycinnamate Cinnamic acid, p-methoxy- EINECS 213-405-4 (E)-3-(4-methoxyphenyl)-acrylic acid LABOTEST-BB LT00108121 2-Propenoic acid, 3-(4-methoxyphenyl)- MFCD00004398 3-(4-methoxyphenyl)prop-2-enoic acid NSC-5303 4-Methoxycinnamic acid, >=98.0% (GC) p-MCA A837404 [ Show all ]
Inchi Key	AFDXODALSZRGIH-QPJJXVBHSA-N
Inchi ID	InChI=1S/C10H10O3/c1-13-9-5-2-8(3-6-9)4-7-10(11)12/h2-7H,1H3,(H,11,12)/b7-4+
PubChem CID	699414
ChEMBL	CHEMBL95770
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
441875	Hydroxycarboxylic acid receptor 2	Q8TDS4	HCAR2	Homo sapiens (Human)	363

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