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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
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Ligand

Name	Zalospirone
Molecular formula	C24H29N5O2
IUPAC name	(1R,2R,6S,7S,8S,11R)-4-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-4-azatetracyclo[5.4.2.02,6.08,11]trideca-9,12-diene-3,5-dione
Molecular weight	419.529
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	1.4
Synonyms	0449O95Z1J GTPL58 ZALOSPIRONE HYDROCHLORIDE WY-47,846 Zalospironum [INN-Latin] (1R,2R,6S,7S,8S,11R)-4-{4-[4-(pyrimidin-2-yl)piperazin-1-yl]butyl}-4-azatetracyclo[5.4.2.0^{2,6}.0^{8,11}]trideca-9,12-diene-3,5-dione CHEMBL3990567 Zalospirona [INN-Spanish] 3aalpha,4,4aalpha,6aalpha,7,7aalpha-Hexahydro-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-4beta,7beta-etheno-1H-cyclobut[f]isoindole-1,3(2H)-dione SCHEMBL247563 Zalospirone [INN] AC1L4TVC Wy-47846 (3ar,4r,4ar,6as,7s,7as)-2-{4-[4-(pyrimidin-2-yl)piperazin-1-yl]butyl}-3a,4,4a,6a,7,7a-hexahydro-1h-4,7-ethenocyclobuta[f]isoindole-1,3(2h)-dione D0OP8W 4,7-Etheno-1H-cyclobut(f)isoindole-1,3(2H)-dione, 3a,4,4a,6a,7,7a-hexahydro-2-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)-, (3aalpha,4alpha,4abeta,6abeta,7alpha,7aalpha)- UNII-0449O95Z1J Zalospironum AC1Q6F21 Zalospirona [ Show all ]
Inchi Key	AERLHOTUXIJQFV-RCPZPFRWSA-N
Inchi ID	InChI=1S/C24H29N5O2/c30-22-20-18-6-7-19(17-5-4-16(17)18)21(20)23(31)29(22)11-2-1-10-27-12-14-28(15-13-27)24-25-8-3-9-26-24/h3-9,16-21H,1-2,10-15H2/t16-,17+,18-,19+,20-,21+
PubChem CID	163925
ChEMBL	N/A
IUPHAR	58
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
553260	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422

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