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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3774425
Molecular formula	C23H26F3N7S
IUPAC name	5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1-[3-(trifluoromethyl)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Molecular weight	489.565
Hydrogen bond acceptor	10
Hydrogen bond donor	0
XlogP	3.2
Synonyms	BDBM50154890 SCHEMBL18453590
Inchi Key	AENHFZZMNBETCL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H26F3N7S/c1-31-21(19-13-27-7-8-28-19)29-30-22(31)34-11-3-9-32-14-16-6-10-33(20(16)15-32)18-5-2-4-17(12-18)23(24,25)26/h2,4-5,7-8,12-13,16,20H,3,6,9-11,14-15H2,1H3
PubChem CID	126534740
ChEMBL	CHEMBL3774425
IUPHAR	N/A
BindingDB	50154890
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
521545	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
521544	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400

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