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Ligand

NameUS8802673, 145
Molecular formulaC16H16F4N4O2
IUPAC nameN-[2-fluoro-4-[(2S)-morpholin-2-yl]phenyl]-5-(2,2,2-trifluoroethoxy)pyrimidin-2-amine
Molecular weight372.324
Hydrogen bond acceptor10
Hydrogen bond donor2
XlogP2.3
SynonymsCHEMBL3641763
BDBM6564
SCHEMBL12609715
Inchi KeyAEBUNQLWKMDXEE-CQSZACIVSA-N
Inchi IDInChI=1S/C16H16F4N4O2/c17-12-5-10(14-8-21-3-4-25-14)1-2-13(12)24-15-22-6-11(7-23-15)26-9-16(18,19)20/h1-2,5-7,14,21H,3-4,8-9H2,(H,22,23,24)/t14-/m1/s1
PubChem CID68325499
ChEMBLCHEMBL3641763
IUPHARN/A
BindingDB6564
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 2
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
3318Trace amine-associated receptor 1Q923Y8Taar1Mus musculus (Mouse)332
3319Trace amine-associated receptor 7bQ923X8Taar7bRattus norvegicus (Rat)358

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