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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL288244
Molecular formula	C23H22Cl2FN3OS
IUPAC name	(3,4-dichlorophenyl)-[4-fluoro-4-[[(6-thiophen-2-ylpyridin-2-yl)methylamino]methyl]piperidin-1-yl]methanone
Molecular weight	478.407
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.8
Synonyms	N-[[1-(3,4-Dichlorobenzoyl)-4-fluoro-4-piperidinyl]methyl]-6-(2-thienyl)-2-pyridinemethanamine SCHEMBL5200248
Inchi Key	ADGCARVTPQCUGH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H22Cl2FN3OS/c24-18-7-6-16(13-19(18)25)22(30)29-10-8-23(26,9-11-29)15-27-14-17-3-1-4-20(28-17)21-5-2-12-31-21/h1-7,12-13,27H,8-11,14-15H2
PubChem CID	10719425
ChEMBL	CHEMBL288244
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
2249	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
2251	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
2250	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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