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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL272694
Molecular formula	C29H32N6OS
IUPAC name	2,10-dimethyl-7-[3-[[4-methyl-5-(2-methylquinolin-5-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-5,6,8,9-tetrahydro-[1,3]oxazolo[4,5-h][3]benzazepine
Molecular weight	512.676
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	5.6
Synonyms	BDBM50411667 SCHEMBL2312420
Inchi Key	ACRMNEFOWLXFLY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H32N6OS/c1-18-9-10-23-24(7-5-8-25(23)30-18)28-32-33-29(34(28)4)37-16-6-13-35-14-11-21-17-26-27(36-20(3)31-26)19(2)22(21)12-15-35/h5,7-10,17H,6,11-16H2,1-4H3
PubChem CID	11663504
ChEMBL	CHEMBL272694
IUPHAR	N/A
BindingDB	50411667
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
1841	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
1839	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
1840	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487

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