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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL103001
Molecular formula	C24H21NO5
IUPAC name	(5S,6R,7R)-5-(1,3-benzodioxol-5-yl)-7-(4-methoxyphenyl)-2-methyl-6,7-dihydro-5H-cyclopenta[b]pyridine-6-carboxylic acid
Molecular weight	403.434
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.8
Synonyms	BDBM50119669 5-Benzo[1,3]dioxol-5-yl-7-(4-methoxy-phenyl)-2-methyl-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid
Inchi Key	ACMPQUAKYNONQE-FDFHNCONSA-N
Inchi ID	InChI=1S/C24H21NO5/c1-13-3-9-17-20(15-6-10-18-19(11-15)30-12-29-18)22(24(26)27)21(23(17)25-13)14-4-7-16(28-2)8-5-14/h3-11,20-22H,12H2,1-2H3,(H,26,27)/t20-,21-,22+/m0/s1
PubChem CID	44333867
ChEMBL	CHEMBL103001
IUPHAR	N/A
BindingDB	50119669
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
1702	Endothelin receptor type B	P24530	EDNRB	Homo sapiens (Human)	442
1701	Endothelin-1 receptor	P25101	EDNRA	Homo sapiens (Human)	427

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