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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL540930
Molecular formula	C31H29ClF4N4O2
IUPAC name	N-[(5-chloro-6-oxo-1H-pyridin-3-yl)-(4-fluorophenyl)methyl]-2-[1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidin-4-yl]acetamide
Molecular weight	601.043
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	5.0
Synonyms	BDBM50296043 N-((5-chloro-6-oxo-1,6-dihydropyridin-3-yl)(4-fluorophenyl)methyl)-2-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)acetamide
Inchi Key	ACHAGBFZZOHGJZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C31H29ClF4N4O2/c32-27-16-23(17-37-30(27)42)29(22-1-5-25(33)6-2-22)38-28(41)15-20-9-12-39(13-10-20)18-21-11-14-40(19-21)26-7-3-24(4-8-26)31(34,35)36/h1-8,11,14,16-17,19-20,29H,9-10,12-13,15,18H2,(H,37,42)(H,38,41)
PubChem CID	11599973
ChEMBL	CHEMBL540930
IUPHAR	N/A
BindingDB	50296043
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
1570	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
1571	Melanin-concentrating hormone receptor 2	Q969V1	MCHR2	Homo sapiens (Human)	340

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