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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL256659
Molecular formula	C22H23F3N6O2S
IUPAC name	8-[3-[[4-methyl-5-(4-methyl-1,3-oxazol-5-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-2-(trifluoromethyl)-6,7,9,10-tetrahydro-[1,3]oxazolo[4,5-i][3]benzazepine
Molecular weight	492.521
Hydrogen bond acceptor	11
Hydrogen bond donor	0
XlogP	3.9
Synonyms	BDBM50423589 SCHEMBL4872412
Inchi Key	ABWRXTVIPWIMTE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H23F3N6O2S/c1-13-17(32-12-26-13)19-28-29-21(30(19)2)34-11-3-8-31-9-6-14-4-5-16-18(15(14)7-10-31)33-20(27-16)22(23,24)25/h4-5,12H,3,6-11H2,1-2H3
PubChem CID	11540474
ChEMBL	CHEMBL256659
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
1257	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
1258	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
1256	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487

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