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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL270853
Molecular formula	C30H34N6OS
IUPAC name	2-methyl-7-[4-[[4-methyl-5-(2-methylquinolin-5-yl)-1,2,4-triazol-3-yl]sulfanyl]butyl]-5,6,8,9-tetrahydro-1H-pyrrolo[3,4-h][3]benzazepin-3-one
Molecular weight	526.703
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	4.4
Synonyms	BDBM50411720
Inchi Key	ABOWDNIHZHLENL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C30H34N6OS/c1-20-9-10-24-25(7-6-8-27(24)31-20)28-32-33-30(35(28)3)38-16-5-4-13-36-14-11-21-17-23-19-34(2)29(37)26(23)18-22(21)12-15-36/h6-10,17-18H,4-5,11-16,19H2,1-3H3
PubChem CID	44454400
ChEMBL	CHEMBL270853
IUPHAR	N/A
BindingDB	50411720
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
1048	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
1046	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
1047	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487

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