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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	methyl 2-amino-4-(3,4-dichlorophenyl)-6,7-dimethyl-5-oxo-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carboxylate
Molecular formula	C18H16Cl2N2O4
IUPAC name	methyl 2-amino-4-(3,4-dichlorophenyl)-6,7-dimethyl-5-oxo-4H-pyrano[3,2-c]pyridine-3-carboxylate
Molecular weight	395.236
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.3
Synonyms	MLS000080585 HMS3308F12 SMR000037435 AKOS001944923 MLS002584136 CHEMBL1392745 MCULE-5566615631 ST50112291 758702-95-3 methyl 2-amino-4-(3,4-dichlorophenyl)-6,7-dimethyl-5-oxo-6-hydro-4H-pyrano[3,2 -c]pyridine-3-carboxylate AKOS016159382 MolPort-000-400-542 HMS2158F03 methyl 2-amino-4-(3,4-dichlorophenyl)-6,7-dimethyl-5-oxo-4H-pyrano[3,2-c]pyridine-3-carboxylate STK166848 AC1LDFKQ [ Show all ]
Inchi Key	ABLMTAFPLXZWFF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H16Cl2N2O4/c1-8-6-12-14(17(23)22(8)2)13(9-4-5-10(19)11(20)7-9)15(16(21)26-12)18(24)25-3/h4-7,13H,21H2,1-3H3
PubChem CID	666250
ChEMBL	CHEMBL1392745
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
463064	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593
944	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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