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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000084280
Molecular formula	C15H17N3O
IUPAC name	4-phenyl-2-piperidin-1-yl-1H-pyrimidin-6-one
Molecular weight	255.321
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	1.8
Synonyms	CHEMBL1485862 MolPort-000-812-350 STK210273 6-phenyl-2-piperidin-1-ylpyrimidin-4(3H)-one 60875-22-1 HMS2363A13 SCHEMBL11736253 AKOS005629655 SR-01000360889-1 6-phenyl-2-(piperidin-1-yl)pyrimidin-4-ol 6-phenyl-2-piperidino-1H-pyrimidin-4-one cid_666391 Oprea1_200129 STK849377 AC1LDFVQ HMS3452D15 SMR000047669 6-phenyl-2-(1-piperidinyl)-1H-pyrimidin-4-one BDBM49016 MolPort-000-510-966 ST50161088 6-phenyl-2-piperidin-1-yl-1H-pyrimidin-4-one 6-phenyl-2-piperidyl-3-hydropyrimidin-4-one F3308-0616 Oprea1_467331 ZINC8579687 AKOS002266915 MCULE-5508209987 SR-01000360889 6-phenyl-2-(piperidin-1-yl)pyrimidin-4(3H)-one [ Show all ]
Inchi Key	ABCUIVDJIWPCLM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H17N3O/c19-14-11-13(12-7-3-1-4-8-12)16-15(17-14)18-9-5-2-6-10-18/h1,3-4,7-8,11H,2,5-6,9-10H2,(H,16,17,19)
PubChem CID	135400155
ChEMBL	N/A
IUPHAR	N/A
BindingDB	49016
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
748	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446

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