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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL338740
Molecular formula	C27H22Cl2N6O2
IUPAC name	2-(2,6-dichlorophenyl)-5-propyl-4-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]pyrazole-3-carboxylic acid
Molecular weight	533.413
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	7.0
Synonyms	L009685 BDBM82436 1-(2,6-Dichlorophenyl)-4-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-3-propyl-1H-pyrazole-5-carboxylic acid L-161,274 SCHEMBL9527287 2-(2,6-Dichloro-phenyl)-5-propyl-4-[2''-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2H-pyrazole-3-carboxylic acid L-161274 BDBM50042550 [ Show all ]
Inchi Key	AAEJZGVELWMPGK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H22Cl2N6O2/c1-2-6-23-20(24(27(36)37)35(32-23)25-21(28)9-5-10-22(25)29)15-16-11-13-17(14-12-16)18-7-3-4-8-19(18)26-30-33-34-31-26/h3-5,7-14H,2,6,15H2,1H3,(H,36,37)(H,30,31,33,34)
PubChem CID	10369813
ChEMBL	CHEMBL338740
IUPHAR	N/A
BindingDB	50042550, 82436
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
139	Type-1 angiotensin II receptor	P34976	AGTR1	Oryctolagus cuniculus (Rabbit)	359
140	Type-2 angiotensin II receptor	P35351	Agtr2	Rattus norvegicus (Rat)	363

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