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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000038563
Molecular formula	C25H31N7O3
IUPAC name	8-[4-[2-(1,2-dimethylindol-3-yl)-2-oxoethyl]piperazin-1-yl]-3-methyl-7-propylpurine-2,6-dione
Molecular weight	477.569
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	2.4
Synonyms	368432-63-7 MCULE-2649306341 ZINC17440323 AC1LCX41 MolPort-002-539-131 CHEMBL1506005 8-[4-[2-(1,2-dimethylindol-3-yl)-2-oxoethyl]piperazin-1-yl]-3-methyl-7-propylpurine-2,6-dione MLS000037405 AKOS005461881 MolPort-006-807-939 HMS2289D19 STK528463 8-{4-[2-(1,2-dimethyl-1H-indol-3-yl)-2-oxoethyl]piperazin-1-yl}-3-methyl-7-propyl-3,7-dihydro-1H-purine-2,6-dione MLS002582005 SCHEMBL8298442 [ Show all ]
Inchi Key	AADHGWGGROCAHV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H31N7O3/c1-5-10-32-21-22(29(4)25(35)27-23(21)34)26-24(32)31-13-11-30(12-14-31)15-19(33)20-16(2)28(3)18-9-7-6-8-17(18)20/h6-9H,5,10-15H2,1-4H3,(H,27,34,35)
PubChem CID	657692
ChEMBL	CHEMBL1506005
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
105	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463

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