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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Neuropeptide Y receptor type 4
Species	Homo sapiens (Human)
Gene	NPY4R
Synonym	NPY4-R neuropeptide Y receptor type 4 pancreatic polypeptide receptor 1 PP1 Y4 receptor
Disease	Obesity Diabetes Schizophrenia
Length	375
Amino acid sequence	MNTSHLLALLLPKSPQGENRSKPLGTPYNFSEHCQDSVDVMVFIVTSYSIETVVGVLGNLCLMCVTVRQKEKANVTNLLIANLAFSDFLMCLLCQPLTAVYTIMDYWIFGETLCKMSAFIQCMSVTVSILSLVLVALERHQLIINPTGWKPSISQAYLGIVLIWVIACVLSLPFLANSILENVFHKNHSKALEFLADKVVCTESWPLAHHRTIYTTFLLLFQYCLPLGFILVCYARIYRRLQRQGRVFHKGTYSLRAGHMKQVNVVLVVMVVAFAVLWLPLHVFNSLEDWHHEAIPICHGNLIFLVCHLLAMASTCVNPFIYGFLNTNFKKEIKALVLTCQQSAPLEESEHLPLSTVHTEVSKGSLRLSGRSNPI
UniProt	P50391
Protein Data Bank	N/A
GPCR-HGmod model	P50391
3D structure model	This predicted structure model is from GPCR-EXP P50391.
BioLiP	N/A
Therapeutic Target Database	T27944
ChEMBL	CHEMBL4877
IUPHAR	307
DrugBank	BE0002418

Ligand

Name	CHEMBL1081469
Molecular formula	C18H18N4S2
IUPAC name	N-[2-[4-(4,5-dihydro-1,3-thiazol-2-ylamino)phenyl]ethyl]-1,3-benzothiazol-2-amine
Molecular weight	354.49
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	4.5
Synonyms	SCHEMBL14000703 BDBM50312007 N-(4-(4,5-dihydrothiazol-2-ylamino)phenethyl)benzo[d]thiazol-2-amine
Inchi Key	FTGKJTDOICYFTN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H18N4S2/c1-2-4-16-15(3-1)22-18(24-16)19-10-9-13-5-7-14(8-6-13)21-17-20-11-12-23-17/h1-8H,9-12H2,(H,19,22)(H,20,21)
PubChem CID	46880224
ChEMBL	CHEMBL1081469
IUPHAR	N/A
BindingDB	50312007
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	<10000.0 nM	PMID19864135	BindingDB,ChEMBL

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