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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	5-hydroxytryptamine receptor 5A
Species	Homo sapiens (Human)
Gene	HTR5A
Synonym	5-HT5alpha 5-HT-5 MR22 Htr5 5-HT-5A 5-HT5A 5HT5- 5-HT5A receptor 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled serotonin receptor 5A [ Show all ]
Disease	N/A
Length	357
Amino acid sequence	MDLPVNLTSFSLSTPSPLETNHSLGKDDLRPSSPLLSVFGVLILTLLGFLVAATFAWNLLVLATILRVRTFHRVPHNLVASMAVSDVLVAALVMPLSLVHELSGRRWQLGRRLCQLWIACDVLCCTASIWNVTAIALDRYWSITRHMEYTLRTRKCVSNVMIALTWALSAVISLAPLLFGWGETYSEGSEECQVSREPSYAVFSTVGAFYLPLCVVLFVYWKIYKAAKFRVGSRKTNSVSPISEAVEVKDSAKQPQMVFTVRHATVTFQPEGDTWREQKEQRAALMVGILIGVFVLCWIPFFLTELISPLCSCDIPAIWKSIFLWLGYSNSFFNPLIYTAFNKNYNSAFKNFFSRQH
UniProt	P47898
Protein Data Bank	N/A
GPCR-HGmod model	P47898
3D structure model	This predicted structure model is from GPCR-EXP P47898.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3426
IUPHAR	10
DrugBank	BE0004688

Ligand

Name	FASDKYOPVNHBLU-UHFFFAOYSA-N
Molecular formula	C10H17N3S
IUPAC name	6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
Molecular weight	211.327
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	1.9
Synonyms	(+/-)2-amino-6-propylamino-4,5,6,7-tetrahydrobenzothiazole 6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine BEN629 I09-0213 N6-Propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine 104617-86-9 AC1Q4W5N CHEMBL76399 MolPort-006-395-737 T5932 (+/-)-2-amino-6-propylamino-4,5,6,7-tetrahydrobenzothiazole 2-amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole AN-5403 HMS3393A21 N6-Propyl-4,5,6,7-tetrahydro-benzothiazole-2,6-diamine (Pramipexole, PPX) (S)-2-Amnio-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole A801038 Benzene,4-chloro-1-(trifluoromethoxy)-2-(trifluoromethyl)- L000492 N~6~-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine dihydrochloride (+/-) 2-amino-6-propylamino-4,5,6,7-tetrahydrobenzothiazole 2,6-benzothiazolediamine, 4,5,6,7-tetrahydro-n6-propyl- AKOS017258887 N'-propyl-4,5,6,7-tetrahydrobenzothiazole-2,6-diamine TRA0068140 (+/-)-2-amino-6-propylamino-4,5,6,7-tetrahydrobenzthiazole BDBM50017550 HMS3657G15 N6-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine AC1L1J65 MCULE-4233228077 SCHEMBL195775 (+/-)-2-amino-6-(N-propylamino)-4,5,6,7-tetrahydrobenzothiazole 2,6-benzothiazolediamine, 4,5,6,7-tetrahydro-N~6~-propyl-, dihydrochloride ALBB-027263 HMS3370D06 N6-Propyl-4,5,6,7-tetrahydro-benzothiazole-2,6-diamine VZ30192 [ Show all ]
Inchi Key	FASDKYOPVNHBLU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C10H17N3S/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8/h7,12H,2-6H2,1H3,(H2,11,13)
PubChem CID	4885
ChEMBL	CHEMBL76399
IUPHAR	N/A
BindingDB	50017550
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	<10000.0 nM	http://pdsp.med.unc.edu/pdsp.php	PDSP

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