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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Gamma-aminobutyric acid type B receptor subunit 1
Species	Homo sapiens (Human)
Gene	GABBR1
Synonym	GPRC3A Gb1 gamma-aminobutyric acid (GABA) B receptor 1 gamma-aminobutyric acid (GABA) B receptor GABABR1 GABAB1 GABA-BR1 GABA-B-R1 GABA-B receptor 1 [ Show all ]
Disease	N/A
Length	961
Amino acid sequence	MLLLLLLAPLFLRPPGAGGAQTPNATSEGCQIIHPPWEGGIRYRGLTRDQVKAINFLPVDYEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPALDGARVDFRCDPDFHLVGSSRSICSQGQWSTPKPHCQVNRTPHSERRAVYIGALFPMSGGWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLKRQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEMTEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPLAYDAIWALALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMAWTLIEQLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISVSVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRNQFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGMDVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNNNEEEKSRLLEKENRELEKIIAEKEERVSELRHQLQSRQQLRSRRHPPTPPEPSGGLPRGPPEPPDRLSCDGSRVHLLYK
UniProt	Q9UBS5
Protein Data Bank	4mqe, 4mqf, 4mr9, 4mrm, 4ms1, 4ms3, 4ms4
GPCR-HGmod model	N/A
3D structure model	This structure is from PDB ID 4mqe.
BioLiP	BL0264367, BL0264359, BL0264358, BL0264357, BL0264356, BL0264366, BL0264368, BL0264369, BL0264370, BL0264371, BL0264365
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2064
IUPHAR	240
DrugBank	BE0000217

Ligand

Name	taurine
Molecular formula	C2H7NO3S
IUPAC name	2-aminoethanesulfonic acid
Molecular weight	125.142
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	-4.1
Synonyms	MLS001332384 AC1L1ARZ NCGC00015997-07 Aminoethylsulfonate NCGC00260069-01 b-Aminoethylsulfonic acid NSC32428 C00245 s2008 CTK0H8760 SR-01000076144-5 DTXSID3021304 tauphon FT-0611241 1-Aminoethane-2-sulfonate I09-0069 2-aminoethane-1-sulfonic acid Lopac-T-0625 2087491-53-8 Tox21_501134 Taurine Hydrochloride Taurine, cell culture tested, meets USP testing specifications Taurineold A0295 NCGC00015997-02 AI3-18307 NCGC00024497-01 AN-22475 NCI60_002814 beta-Aminoethylsulfonate Pharmakon1600-01505463 CCG-205208 SCHEMBL23068 T 0625 Ethanesulfonic acid, 2-amino- HMS2233D19 107-35-7, 2-Aminoethanesulfonic acid KB-259903 2-AminoethanesulfonicAcid LS-439 TL8000260 UNII-1EQV5MLY3D Taurina [Spanish] Taurine, 99% Taurine, PharmaGrade, Ajinomoto, Manufactured under appropriate GMP controls for pharma or biopharmaceutical production, suitable for cell culture MLS000859681 AB00443712_10 NCGC00015997-05 AM20080018 NCGC00024497-04 AS-13587 NSC-32428 bmse000805 RP17828 CHEMBL239243 SR-01000076144-1 DSSTox_GSID_21304 taufon F2191-0280 HSDB 8167 2-amino-ethanesulfonic acid KSC178O6B 2-Aminoethylsulfonic acid Tox21_110277_1 Z1317839154 Taurine (JP17/USP/INN) Taurine, >=99.0% (T) Taurine, Vetec(TM) reagent grade, >=99% MolPort-000-006-300 AC1Q54NS NCGC00015997-08 aminoethylsulfonic acid NCGC00261819-01 B1846 NSC759150 C2H7NO3S SBI-0051101.P002 D00047 ST2409585 EC 203-483-8 tauric acid GTPL2379 1-Aminoethane-2-sulfonic acid I815 2-aminoethanesulfonic acid Lopac0_001134 2aminoethanesulfonic acid Taurinum TR-001805 Taurine [INN] Taurine, certified reference material, TraceCERT(R) AB00443712-07 NCGC00015997-03 AJ-45668 NCGC00024497-02 ANW-15782 NE10562 beta-Aminoethylsulfonic acid PubChem18250 CCRIS 4721 SMR000326743 DB01956 T-130 Ethanesulfonic acid, 2-amino- (9CI) HMS3263D09 1365481-05-5 KS-00000ADB 2-aminoethyl sulfonate MCULE-6041857208 Tocris-0209 WLN: Z2SWQ Taurine, >=98%, FG Taurine, SAJ first grade, >=98.5% MLS001332383 AB1002120 NCGC00015997-06 Aminoethanesulfonic acid NCGC00024497-05 b-Aminoethylsulfonate NSC-759150 bmse000863 RTR-001805 CS-2397 SR-01000076144-3 DSSTox_RID_76069 Taukard FEMA No. 3813 .beta.-Aminoethylsulfonic acid HY-B0351 2-aminoethane sulfonic acid L-Taurine 2-Sulfoethylamine Tox21_202520 ZINC3809490 Taurine (TN) Taurine, BioUltra, >=99.5% (T) Taurine,(S) NCGC00015997-01 ACMC-2098vs NCGC00015997-10 Aminoethylsulfonic acid (JAN) NCI-C60606 BDBM50357220 O-Due CAS-107-35-7 SC-19115 D0C6IE STL197941 EINECS 203-483-8 HMS2093L13 107-35-7 J-508042 2-aminoethanesulfonic acid. LP01134 91105-79-2 Taurinum [Latin] TRA-0183757 Taurina Taurine [USP:INN:BAN] Taurine, Pharmaceutical Secondary Standard; Certified Reference Material AB00443712_09 NCGC00015997-04 AKOS005208848 NCGC00024497-03 ARONIS27193 NSC 32428 bmse000120 RKL10149 CHEBI:15891 SR-01000076144 DSSTox_CID_1304 TAU EU-0101134 HMS3370J18 1EQV5MLY3D KS-000048OD 2-Aminoethylsulfonate MFCD00008197 Tox21_110277 XOAAWQZATWQOTB-UHFFFAOYSA-N Taurine (8CI) Taurine, >=99% Taurine, United States Pharmacopeia (USP) Reference Standard [ Show all ]
Inchi Key	XOAAWQZATWQOTB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6)
PubChem CID	1123
ChEMBL	N/A
IUPHAR	N/A
BindingDB	N/A
DrugBank	DB01956
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
	N/A	N/A	DrugBank

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