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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Putative P2Y purinoceptor 10
Species	Homo sapiens (Human)
Gene	P2RY10
Synonym	P2Y-like receptor P2RY10 purinergic receptor P2Y purinergic receptor P2Y, G-protein coupled 10 purinergic receptor P2Y10 P2Y10 [ Show all ]
Disease	N/A
Length	339
Amino acid sequence	MANLDKYTETFKMGSNSTSTAEIYCNVTNVKFQYSLYATTYILIFIPGLLANSAALWVLCRFISKKNKAIIFMINLSVADLAHVLSLPLRIYYYISHHWPFQRALCLLCFYLKYLNMYASICFLTCISLQRCFFLLKPFRARDWKRRYDVGISAAIWIVVGTACLPFPILRSTDLNNNKSCFADLGYKQMNAVALVGMITVAELAGFVIPVIIIAWCTWKTTISLRQPPMAFQGISERQKALRMVFMCAAVFFICFTPYHINFIFYTMVKETIISSCPVVRIALYFHPFCLCLASLCCLLDPILYYFMASEFRDQLSRHGSSVTRSRLMSKESGSSMIG
UniProt	O00398
Protein Data Bank	N/A
GPCR-HGmod model	O00398
3D structure model	This predicted structure model is from GPCR-EXP O00398.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3562166
IUPHAR	165
DrugBank	N/A

Ligand

Name	CHEMBL3577147
Molecular formula	C18H36NO9P
IUPAC name	(2S)-2-amino-3-[[(2R)-3-dodecanoyloxy-2-hydroxypropoxy]-hydroxyphosphoryl]oxypropanoic acid
Molecular weight	441.458
Hydrogen bond acceptor	10
Hydrogen bond donor	4
XlogP	-0.2
Synonyms	LPS(12:0) LPS(12:0/0:0) BDBM50096354 LMGP03050008 1-dodecanoyl-glycero-3-phosphoserine PS(12:0/0:0) [ Show all ]
Inchi Key	OBMNLLRGDUINGE-CVEARBPZSA-N
Inchi ID	InChI=1S/C18H36NO9P/c1-2-3-4-5-6-7-8-9-10-11-17(21)26-12-15(20)13-27-29(24,25)28-14-16(19)18(22)23/h15-16,20H,2-14,19H2,1H3,(H,22,23)(H,24,25)/t15-,16+/m1/s1
PubChem CID	52926276
ChEMBL	CHEMBL3577147
IUPHAR	N/A
BindingDB	50096354
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
EC50	933.0 nM	PMID25970039	BindingDB
EC50	933.25 nM	PMID25970039	ChEMBL
EC50	940.0 nM	PMID25970039	BindingDB,ChEMBL

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