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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Beta-2 adrenergic receptor
Species	Cavia porcellus (Guinea pig)
Gene	Adrb2
Synonym	Beta-2 adrenoceptor Beta-2 adrenoreceptor
Disease	N/A for non-human GPCRs
Length	418
Amino acid sequence	MGHLGNGSDFLLAPNASHAPDHNVTRERDEAWVVGMAIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMNMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWVVSGLTSFLPIQMHWYRATHKDAINCYAEETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAKKQLQKIDRSEGRFHTQNLSQVEQDGRSGHGLRRSSKFYLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSALKAYGNDCSSNSNGKTDYTGEPNVCHQGQEKERELLCEDPPGTEDLVSCPGTVPSDSIDSQGRNYSTNDSLL
UniProt	Q8K4Z4
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5414
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL323990
Molecular formula	C23H30N2O5S2
IUPAC name	4-hydroxy-7-[2-[2-[3-[(2S)-1-phenylpropan-2-yl]oxypropylsulfonyl]ethylamino]ethyl]-3H-1,3-benzothiazol-2-one
Molecular weight	478.622
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	3.1
Synonyms	N/A
Inchi Key	CPEZPTWGCSCZRH-KRWDZBQOSA-N
Inchi ID	InChI=1S/C23H30N2O5S2/c1-17(16-18-6-3-2-4-7-18)30-13-5-14-32(28,29)15-12-24-11-10-19-8-9-20(26)21-22(19)31-23(27)25-21/h2-4,6-9,17,24,26H,5,10-16H2,1H3,(H,25,27)/t17-/m0/s1
PubChem CID	44339137
ChEMBL	CHEMBL323990
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Beta2 duration	180.0 min	PMID12852752	ChEMBL

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