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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	C-C chemokine receptor type 3
Species	Rattus norvegicus (Rat)
Gene	Ccr3
Synonym	CKR3 chemokine (C-C motif) receptor 3 CD193 CCR3 CCR-3 CC-CKR-3 CC CKR3 C-C CKR-3 MIP-1alphaRL-2 (mouse) [ Show all ]
Disease	N/A for non-human GPCRs
Length	359
Amino acid sequence	MASNEEELKTVVETFETTPYEYEWAPPCEKVSIRELGSWLLPPLYSLVFIVGLLGNMMVVLILIKYRKLQIMTNIYLLNLAISDLLFLFTVPFWIHYVLWNEWGFGHCMCKMLSGLYYLALYSEIFFIILLTIDRYLAIVHAVLALRARTVTFATITSIITWGFAVLAALPEFIFHESQDNFGDLSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIQLIFVVMIVFFIFWTPYNLVLLLSAFHSTFLETSCQQSIHLDLAMQVTEVITHTHCCINPIIYAFVGERFRKHLRLFFHRNVAIYLRKYISFLPGEKLERTSSVSPSTGEQEISVVF
UniProt	O54814
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3928
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL3355941
Molecular formula	C25H28F2N2O2S
IUPAC name	ethyl 6-fluoro-3-[1-[3-(4-fluorophenyl)sulfanylpropyl]piperidin-4-yl]-1H-indole-2-carboxylate
Molecular weight	458.568
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	5.9
Synonyms	BDBM50041183
Inchi Key	ZDNRSFQTWFIIDN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H28F2N2O2S/c1-2-31-25(30)24-23(21-9-6-19(27)16-22(21)28-24)17-10-13-29(14-11-17)12-3-15-32-20-7-4-18(26)5-8-20/h4-9,16-17,28H,2-3,10-15H2,1H3
PubChem CID	118721192
ChEMBL	CHEMBL3355941
IUPHAR	N/A
BindingDB	50041183
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	100.0 nM	PMID25497216	BindingDB,ChEMBL

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