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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Somatostatin receptor type 5
Species	Homo sapiens (Human)
Gene	SSTR5
Synonym	SOMATO SS-5-R SS5-R SS5R SST5 receptor
Disease	N/A
Length	364
Amino acid sequence	MEPLFPASTPSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTLVIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRLVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVFADVQEGGTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGVRVGCVRRRSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVILSYANSCANPVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPPAHRAAANGLMQTSKL
UniProt	P35346
Protein Data Bank	N/A
GPCR-HGmod model	P35346
3D structure model	This predicted structure model is from GPCR-EXP P35346.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1792
IUPHAR	359
DrugBank	BE0002147

Ligand

Name	CHEMBL3218121
Molecular formula	C36H50N6O5
IUPAC name	1-(4-aminobutyl)-9-benzyl-13-[(2R)-2-hydroxypropyl]-5-[2-(1H-indol-3-yl)ethyl]-1,5,9,13-tetrazacyclohexadecane-2,6,10,14-tetrone
Molecular weight	646.833
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	0.8
Synonyms	N/A
Inchi Key	CFQNIMHZPDPNQN-MUUNZHRXSA-N
Inchi ID	InChI=1S/C36H50N6O5/c1-28(43)26-41-23-17-36(47)42(27-29-9-3-2-4-10-29)24-16-34(45)40(20-13-30-25-38-32-12-6-5-11-31(30)32)22-14-33(44)39(19-8-7-18-37)21-15-35(41)46/h2-6,9-12,25,28,38,43H,7-8,13-24,26-27,37H2,1H3/t28-/m1/s1
PubChem CID	90665459
ChEMBL	CHEMBL3218121
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
Ki	28000.0 nM	MedChemComm, (2012) 3:12:1531	ChEMBL

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