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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	2-oxoglutarate receptor 1
Species	Homo sapiens (Human)
Gene	OXGR1
Synonym	Alpha-ketoglutarate receptor 1 P2Y15 P2Y-like nucleotide receptor P2Y-like GPCR P2Y purinoceptor 15 P2RY15 oxoglutarate receptor GPR99 G-protein coupled receptor 99 G-protein coupled receptor 80 G protein-coupled receptor 99 G protein-coupled receptor 80 2-oxoglutarate receptor 1 GPR80 [ Show all ]
Disease	N/A
Length	337
Amino acid sequence	MNEPLDYLANASDFPDYAAAFGNCTDENIPLKMHYLPVIYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNLACTDLLYLTSLPFLIHYYASGENWIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVIIHPMSCFSIHKTRCAVVACAVVWIISLVAVIPMTFLITSTNRTNRSACLDLTSSDELNTIKWYNLILTATTFCLPLVIVTLCYTTIIHTLTHGLQTDSCLKQKARRLTILLLLAFYVCFLPFHILRVIRIESRLLSISCSIENQIHEAYIVSRPLAALNTFGNLLLYVVVSDNFQQAVCSTVRCKVSGNLEQAKKISYSNNP
UniProt	Q96P68
Protein Data Bank	N/A
GPCR-HGmod model	Q96P68
3D structure model	This predicted structure model is from GPCR-EXP Q96P68.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2150840
IUPHAR	162
DrugBank	N/A

Ligand

Name	CHEMBL2153440
Molecular formula	C25H22ClN3O
IUPAC name	N-[[4-(3-chlorophenyl)phenyl]methyl]-4-(1,8-naphthyridin-2-yl)butanamide
Molecular weight	415.921
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	5.1
Synonyms	BDBM50393117
Inchi Key	WQQRCIURTFHROP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H22ClN3O/c26-22-6-1-4-21(16-22)19-11-9-18(10-12-19)17-28-24(30)8-2-7-23-14-13-20-5-3-15-27-25(20)29-23/h1,3-6,9-16H,2,7-8,17H2,(H,28,30)
PubChem CID	71462027
ChEMBL	CHEMBL2153440
IUPHAR	N/A
BindingDB	50393117
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	7000.0 nM	PMID21571530	BindingDB,ChEMBL

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