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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Cholecystokinin receptor type A
Species	Rattus norvegicus (Rat)
Gene	Cckar
Synonym	CCK-A receptor CCK-AR CCK1 receptor CCK1-R cholecystokinin receptor type A cholecystokinin-1 receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	444
Amino acid sequence	MSHSPARQHLVESSRMDVVDSLLMNGSNITPPCELGLENETLFCLDQPQPSKEWQSALQILLYSIIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLLPGIVMVVAYGLISLELYQGIKFDASQKKSAKEKKPSTGSSTRYEDSDGCYLQKSRPPRKLELQQLSSGSGGSRLNRIRSSSSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAEKHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGVRGEVGEEEDGRTIRALLSRYSYSHMSTSAPPP
UniProt	P30551
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2871
IUPHAR	76
DrugBank	N/A

Ligand

Name	CHEMBL536938
Molecular formula	C27H41Cl3N4O3
IUPAC name	N-[1-(8-azaspiro[4.5]decan-8-yl)-5-[2-(diethylamino)ethylamino]-1,5-dioxopentan-2-yl]-3,5-dichlorobenzamide;hydrochloride
Molecular weight	576.0
Hydrogen bond acceptor	4
Hydrogen bond donor	3
XlogP	None
Synonyms	N/A
Inchi Key	BJGLBQOYYWBKAV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H40Cl2N4O3.ClH/c1-3-32(4-2)16-13-30-24(34)8-7-23(31-25(35)20-17-21(28)19-22(29)18-20)26(36)33-14-11-27(12-15-33)9-5-6-10-27;/h17-19,23H,3-16H2,1-2H3,(H,30,34)(H,31,35);1H
PubChem CID	45262976
ChEMBL	CHEMBL536938
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. Partition coefficient log P of this ligand is not available.

Experimental Data

Parameter	Value	Reference	Database source
IC50	18500.0 nM	Bioorg. Med. Chem. Lett., (1993) 3:5:861	ChEMBL

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