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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Beta-2 adrenergic receptor
Species	Cavia porcellus (Guinea pig)
Gene	Adrb2
Synonym	Beta-2 adrenoceptor Beta-2 adrenoreceptor
Disease	N/A for non-human GPCRs
Length	418
Amino acid sequence	MGHLGNGSDFLLAPNASHAPDHNVTRERDEAWVVGMAIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMNMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWVVSGLTSFLPIQMHWYRATHKDAINCYAEETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAKKQLQKIDRSEGRFHTQNLSQVEQDGRSGHGLRRSSKFYLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSALKAYGNDCSSNSNGKTDYTGEPNVCHQGQEKERELLCEDPPGTEDLVSCPGTVPSDSIDSQGRNYSTNDSLL
UniProt	Q8K4Z4
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5414
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL322722
Molecular formula	C22H30N2O5S3
IUPAC name	4-hydroxy-7-[2-[3-[2-[3-(5-methylthiophen-2-yl)propoxy]ethylsulfonyl]propylamino]ethyl]-3H-1,3-benzothiazol-2-one
Molecular weight	498.671
Hydrogen bond acceptor	8
Hydrogen bond donor	3
XlogP	3.2
Synonyms	N/A
Inchi Key	BBUIQTAEZIRYKH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H30N2O5S3/c1-16-5-7-18(30-16)4-2-12-29-13-15-32(27,28)14-3-10-23-11-9-17-6-8-19(25)20-21(17)31-22(26)24-20/h5-8,23,25H,2-4,9-15H2,1H3,(H,24,26)
PubChem CID	44338979
ChEMBL	CHEMBL322722
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Beta2 duration	<180.0 min	PMID12852752	ChEMBL

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