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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Beta-2 adrenergic receptor
Species	Cavia porcellus (Guinea pig)
Gene	Adrb2
Synonym	Beta-2 adrenoceptor Beta-2 adrenoreceptor
Disease	N/A for non-human GPCRs
Length	418
Amino acid sequence	MGHLGNGSDFLLAPNASHAPDHNVTRERDEAWVVGMAIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMNMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWVVSGLTSFLPIQMHWYRATHKDAINCYAEETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAKKQLQKIDRSEGRFHTQNLSQVEQDGRSGHGLRRSSKFYLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSALKAYGNDCSSNSNGKTDYTGEPNVCHQGQEKERELLCEDPPGTEDLVSCPGTVPSDSIDSQGRNYSTNDSLL
UniProt	Q8K4Z4
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5414
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL287651
Molecular formula	C17H23NO2
IUPAC name	1-(2-methylpropylamino)-3-naphthalen-1-yloxypropan-2-ol
Molecular weight	273.376
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	3.5
Synonyms	AKOS016328044 1-(2-methylpropylamino)-3-naphthalen-1-yloxypropan-2-ol PROPRANOLOL, dl AC1L2Y2B BDBM81886 3-[(2-methylpropyl)amino]-1-naphthyloxypropan-2-ol ST50794004 AKOS002279435 CAS_3506-09-0 MCULE-8872406706 [ Show all ]
Inchi Key	BBNJVDLLHMJGCV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H23NO2/c1-13(2)10-18-11-15(19)12-20-17-9-5-7-14-6-3-4-8-16(14)17/h3-9,13,15,18-19H,10-12H2,1-2H3
PubChem CID	105110
ChEMBL	CHEMBL287651
IUPHAR	N/A
BindingDB	81886
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Kd	1.259 nM	PMID6130153	ChEMBL
Kd	1.26 nM	PMID6130153	BindingDB

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