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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Alpha-1A adrenergic receptor
Species	Bos taurus (Bovine)
Gene	ADRA1A
Synonym	Alpha-1A adrenoceptor Alpha-1A adrenoreceptor Alpha-1C adrenergic receptor
Disease	N/A for non-human GPCRs
Length	466
Amino acid sequence	MVFLSGNASDSSNCTHPPPPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNVWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQKRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQINEEPGYVLFSALGSFYVPLTIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAQVGGSGVTSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFRPSETVFKIAFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLRRKQSSKHTLGYTLHAPSHVLEGQHKDLVRIPVGSAETFYKISKTDGVCEWKIFSSLPRGSARMAVARDPSACTTARVRSKSFLQVCCCLGPSTPSHGENHQIPTIKIHTISLSENGEEV
UniProt	P18130
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4892
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	85386-90-9
Molecular formula	C10H14FN3
IUPAC name	1-(3-fluoropyridin-2-yl)-4-methylpiperazine
Molecular weight	195.241
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	1.2
Synonyms	KZNJAAWCEFRAPW-UHFFFAOYSA-N ZINC36237989 BDBM50026633 D0MH0S 1-Methyl-4-(3-fluoro-2-pyridinyl)piperazine Piperazine, 1-(3-Fluoro-2-pyridinyl)-4-methyl- (9ci) AKOS025286419 1-(3-Fluoro-pyridin-2-yl)-4-methyl-piperazine J-523963 SCHEMBL10964078 AM87258 CHEMBL280514 1-(3-fluoropyridin-2-yl)-4-methylpiperazine [ Show all ]
Inchi Key	KZNJAAWCEFRAPW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C10H14FN3/c1-13-5-7-14(8-6-13)10-9(11)3-2-4-12-10/h2-4H,5-8H2,1H3
PubChem CID	13298530
ChEMBL	CHEMBL280514
IUPHAR	N/A
BindingDB	50026633
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	490.0 nM	PMID6139479, PMID6088770	BindingDB,ChEMBL

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