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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
YNYDEVLEKSILFYEAERSGDLPANNRIPYRGDSALGDQGNQGQDLTGGWYDAGDHVKFGFPMAFATTTLAWGILEFRDG
YEAAGQYNLALDSIRWTLNYFLKAHVSDNEFYGQVGDANTDHAYWGRPEDMTMERPAWSISPSAPGSDLAAETAAALAAG
YLVFRDSDAAFANNLLAHSRTLYDFALNNRGIYSQSISNAAGFYASSAYEDELAWGAAWLYRATEEQEYLDRAYEFGTTT
NTAWAYDWNEKIVGYQLLLTTSAGQTDFLPRVENFLRNWFPGGSVQYTPLGLAWLAQWGPNRYAANAAFIALVSAKYNIL
ASESEQFARSQIHYMLGDAGRSYVVGFGNNPPQQPHHRSSSCPDEPAECDWDEFNQPGPNYQILYGALVGGPDQNDQFED
LRSDYIRNEVANDYNAGFQGAVAALRAIQLRD

The query sequence (length=432) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3wc3:A 435 432 0.9977 0.9908 0.9977 0.0 8ihw:A, 8ihx:A, 8ihy:A
2 4zg8:A 426 425 0.6319 0.6408 0.6424 0.0 4zg8:B, 4zh5:A, 4zh5:B
3 1ksc:A 433 432 0.5648 0.5635 0.5648 2.06e-170 1ksd:A
4 8u49:A 615 444 0.5069 0.3561 0.4932 1.39e-128 8u4a:A, 8u4f:A
5 1js4:A 605 444 0.5069 0.3620 0.4932 1.01e-126 1js4:B, 1tf4:A, 1tf4:B, 3tf4:A, 3tf4:B, 4tf4:A, 4tf4:B
6 2xfg:A 446 448 0.4444 0.4305 0.4286 1.14e-117
7 4dod:A 454 443 0.4468 0.4251 0.4357 9.72e-112 4doe:A
8 1g87:B 613 442 0.4375 0.3083 0.4276 4.46e-107 1g87:A, 1ga2:A, 1ga2:B, 1k72:A, 1k72:B, 1kfg:A, 1kfg:B
9 7unp:A 608 446 0.4398 0.3125 0.4260 2.43e-102 7v0i:C, 7v0i:A, 7v0i:B, 7v0j:A, 7v0j:B, 7v0j:C
10 1ia7:A 431 435 0.3773 0.3782 0.3747 8.81e-91 1ia6:A
11 2yik:A 493 484 0.4074 0.3570 0.3636 1.25e-89
12 5gxx:A 600 449 0.4097 0.2950 0.3942 2.55e-89 5gxx:B, 5gxy:A, 5gxy:B, 5gxz:A, 5gxz:B, 5gy0:A, 5gy0:B, 5gy1:A, 5gy1:B
13 4cj1:A 544 425 0.2454 0.1949 0.2494 2.14e-15 4cj0:A, 1clc:A
14 3gzk:A 531 469 0.2662 0.2166 0.2452 1.70e-13 5e2j:A, 5e2j:B, 3ez8:A, 3h2w:A, 3h3k:A, 3rx5:A, 3rx7:A, 3rx8:A
15 3x17:B 548 411 0.2616 0.2062 0.2749 2.13e-12 3x17:A
16 1rq5:A 602 427 0.2639 0.1894 0.2670 4.64e-12
17 6dht:A 547 443 0.2361 0.1865 0.2302 4.56e-08
18 5u2o:A 543 360 0.2130 0.1694 0.2556 2.95e-07
19 6fhj:A 979 16 0.0278 0.0123 0.7500 0.95 6fhn:A
20 8gwe:A 931 100 0.0579 0.0269 0.2500 5.8 7aap:A, 7b3b:A, 7b3c:A, 7b3d:A, 7btf:A, 7bv1:A, 7bv2:A, 7bw4:A, 7bzf:A, 7c2k:A, 7ctt:A, 7cxm:A, 7cxn:A, 7cyq:A, 7d4f:A, 7dfg:A, 7dfh:A, 7doi:A, 7dok:A, 7dte:A, 7ed5:A, 7egq:A, 7egq:N, 7eiz:A, 8gw1:A, 8gwb:A, 8gwf:A, 8gwg:A, 8gwi:A, 8gwk:A, 8gwm:A, 8gwn:A, 8gwo:A, 8gy6:A, 7krn:A, 7kro:A, 7krp:A, 7l1f:A, 6nur:A, 7oyg:A, 7oyg:D, 7ozu:A, 7ozv:A, 7rdx:A, 7rdy:A, 7rdz:A, 7re0:A, 7re1:A, 7re2:A, 7re3:A, 7re3:G, 8sq9:A, 8sqj:A, 8sqk:A, 7uo4:A, 7uo7:A, 7uo9:A, 7uob:A, 7uoe:A, 6xez:A, 6xqb:A, 6yyt:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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