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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VKDTYTDRLDDWNGIIAGNQYYDSKNDQMAKLNQELEGKVADSLSSISSQADRIYLWEKFSNYKTSANLTATYRKLEEMA
KQVTNPSSRYYQDETVVRTVRDSMEWMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFV
PDPEHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFYQDGSYIDHTNVAYTGAYG
NVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPLLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMS
EGETKQRLQSLVKTIVQSDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGFGLSLF
SSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTETDAKRADSDTGKVLPSAFVGTSKLDDA
NATATMDFTNWNQTLTAHKSWFMLKDKIAFLGSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQ
SVFLESSDSKKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYMLIPNVDRATFNQM
IKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLKRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKK
L

The query sequence (length=721) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1ojn:A 722 721 0.9986 0.9972 0.9986 0.0 2brp:A, 2brw:A, 2brw:B, 1c82:A, 1egu:A, 1f9g:A, 1loh:A, 1lxk:A, 1n7q:A, 1n7r:A, 1ojm:A, 1ojo:A, 1ojp:A, 1w3y:A
2 1i8q:A 814 727 0.5409 0.4791 0.5365 0.0 1lxm:A
3 2e22:A 752 675 0.2594 0.2487 0.2770 1.09e-90 1j0m:A, 1j0n:A, 1x1i:A, 1x1j:A
4 1rwc:A 754 653 0.2552 0.2440 0.2818 1.43e-82 1rwf:A, 1rwg:A, 1rwh:A
5 6f2p:A 1040 673 0.2802 0.1942 0.3001 5.48e-82
6 2wda:A 742 609 0.2150 0.2089 0.2545 5.98e-56
7 1cb8:A 674 594 0.1969 0.2107 0.2391 1.17e-24 1hm2:A, 1hm3:A, 1hmu:A, 1hmw:A
8 2q1f:A 991 198 0.0666 0.0484 0.2424 1.0 2q1f:B
9 6z9l:A 744 117 0.0458 0.0444 0.2821 2.3 6z9k:A, 6z9k:B
10 8beq:A 534 69 0.0347 0.0468 0.3623 2.5 8beq:B, 8bes:A, 8bes:B, 8bes:C, 8bes:D, 8bet:A, 8bet:B, 8bet:C, 8bet:D, 8beu:A, 8beu:B, 8beu:C, 8beu:D
11 6gfu:A 386 97 0.0388 0.0725 0.2887 2.8 5w76:A, 5w7q:A
12 7p8n:B 613 77 0.0291 0.0343 0.2727 6.5 7p5h:B, 7p5h:E, 7p5h:b, 7p5h:e, 7p8n:b, 7p91:b, 7p91:B, 7p92:B
13 6km9:B 845 128 0.0416 0.0355 0.2344 7.5 6km9:A, 6kma:A, 6kma:B, 6kma:C, 6kma:D
14 8s1u:H 518 23 0.0166 0.0232 0.5217 8.5
15 8p5d:LG0 199 42 0.0194 0.0704 0.3333 9.1 8p60:LG0, 8p60:KG0, 7qca:LG0
16 7aqc:R 558 23 0.0166 0.0215 0.5217 9.3 7aqd:R, 7as8:0, 7as9:0, 7asa:0, 7ope:0

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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