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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
VGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKLKDPANFQYPAESVLAYKEGHL
SPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERVFIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGI
HGDMNVILWPIQSGILHFCGFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMKK
EVQDEEKNKKFGLSVGHHLGKSIPTDNQIKAR

The query sequence (length=272) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5ea2:C 276 272 1.0000 0.9855 1.0000 0.0 5a4k:A, 5a4k:B, 5a4k:C, 5a4k:D, 8c9j:A, 8c9j:B, 8c9j:C, 8c9j:D, 4cet:A, 4cf6:A, 4cf6:B, 1d4a:A, 1d4a:B, 1d4a:D, 1d4a:C, 1dxo:A, 1dxo:C, 1dxo:B, 1dxo:D, 5ea2:A, 5ea2:E, 5ea2:G, 5eai:A, 5eai:B, 5eai:C, 5eai:D, 5eai:E, 5eai:F, 5eai:G, 5eai:H, 5eai:I, 5eai:J, 5eai:K, 5eai:L, 5eai:M, 5eai:N, 2f1o:A, 2f1o:C, 2f1o:B, 2f1o:D, 2f1o:E, 2f1o:F, 2f1o:G, 2f1o:H, 5fuq:A, 5fuq:B, 6fy4:A, 6fy4:B, 6fy4:C, 6fy4:D, 1gg5:A, 1gg5:C, 1gg5:B, 1gg5:D, 1h66:A, 1h66:C, 1h66:B, 1h66:D, 1h69:A, 1h69:C, 1h69:B, 1h69:D, 3jsx:A, 3jsx:B, 3jsx:C, 3jsx:D, 3jsx:E, 3jsx:G, 3jsx:F, 3jsx:H, 1kbo:A, 1kbo:C, 1kbo:B, 1kbo:D, 1kbq:A, 1kbq:C, 1kbq:B, 1kbq:D, 6llc:A, 6llc:D, 6llc:B, 6llc:F, 6llc:C, 6llc:E, 6llc:G, 6llc:H, 6llc:I, 6llc:J, 6llc:K, 6llc:L, 8ok0:A, 8ok0:D, 8ok0:B, 8ok0:C, 8pqn:A, 8pqn:B, 8pqn:C, 8pqn:D, 1qbg:A, 1qbg:B, 1qbg:C, 1qbg:D, 8rfm:A, 8rfm:B, 8rfm:C, 8rfm:D, 8rfn:A, 8rfn:B, 8rfn:C, 8rfn:D
2 1dxq:A 273 271 0.8566 0.8535 0.8598 7.06e-180 1dxq:C, 1dxq:B, 1dxq:D, 1qrd:A, 1qrd:B
3 4fgl:D 233 219 0.3934 0.4592 0.4886 7.13e-74 5buc:A, 5buc:B, 2bzs:A, 2bzs:B, 4fgj:A, 4fgj:B, 4fgk:A, 4fgk:B, 4fgl:A, 4fgl:B, 4fgl:C, 3fw1:A, 3g5m:A, 3g5m:B, 3gam:A, 3gam:B, 4gqi:A, 4gqi:B, 4gr9:A, 4gr9:B, 5lbt:A, 5lbt:B, 5lbu:A, 5lbu:B, 5lbw:A, 5lbw:B, 5lby:A, 5lby:B, 5lbz:A, 5lbz:B, 3nfr:A, 3nfr:B, 3nhf:A, 3nhf:B, 3nhj:A, 3nhj:B, 3nhk:A, 3nhk:B, 3nhl:A, 3nhl:B, 3nhp:A, 3nhp:B, 3nhr:A, 3nhr:B, 3nhs:A, 3nhs:B, 3nhu:A, 3nhu:B, 3nhw:A, 3nhw:B, 3nhy:A, 3nhy:B, 3o2n:A, 3o2n:B, 7o4d:A, 7o4d:B, 3o73:A, 3o73:B, 3ovm:A, 3ovm:B, 3owh:A, 3owh:B, 3owx:A, 3owx:B, 3ox1:A, 3ox1:B, 3ox2:A, 3ox2:B, 3ox3:A, 3ox3:B, 2qmy:A, 2qmy:B, 2qmz:A, 2qmz:B, 4qod:A, 4qod:B, 4qoe:A, 4qoe:B, 4qof:A, 4qof:B, 4qog:A, 4qog:B, 4qoh:A, 4qoh:B, 4qoi:A, 4qoi:B, 4qoj:A, 4qoj:B, 1qr2:A, 1qr2:B, 2qr2:A, 2qr2:B, 2qwx:A, 2qwx:B, 2qx4:A, 2qx4:B, 2qx6:A, 2qx6:B, 2qx8:A, 2qx8:B, 2qx9:A, 2qx9:B, 1sg0:A, 1sg0:B, 3te7:A, 3te7:B, 3tem:A, 3tem:B, 3tzb:A, 3tzb:B, 3tzb:C, 3tzb:D, 4u7f:A, 4u7f:B, 4u7g:A, 4u7g:B, 4u7h:A, 4u7h:B, 3uxe:A, 3uxe:B, 3uxh:A, 3uxh:B, 4xdg:A, 4xdg:B, 4xdh:A, 4xdh:B, 1xi2:A, 1xi2:B, 4zvk:A, 4zvk:B, 4zvl:A, 4zvl:B, 4zvm:A, 4zvm:B, 4zvn:A, 4zvn:B, 1zx1:A, 1zx1:B
4 4gi5:B 261 227 0.3272 0.3410 0.3921 2.25e-42 4gi5:A
5 4f8y:A 196 156 0.1985 0.2755 0.3462 8.16e-15 4f8y:B, 4f8y:C, 4f8y:D, 3lcm:A, 3lcm:B, 3lcm:C, 3lcm:D
6 3l9w:B 357 104 0.1360 0.1036 0.3558 5.33e-14 3eyw:A, 3eyw:B, 3l9w:A
7 3l9x:A 336 104 0.1360 0.1101 0.3558 5.92e-14 3l9x:B
8 4r81:A 199 162 0.1691 0.2312 0.2840 4.56e-13 4r81:B, 4r81:C, 4r81:D
9 5lva:A 174 150 0.1471 0.2299 0.2667 4.23e-10 5lva:B
10 3f2v:A 174 88 0.1066 0.1667 0.3295 7.26e-09
11 6dxp:A 206 154 0.1507 0.1990 0.2662 7.71e-05 6dxp:C, 6dxp:B, 6dxp:D, 8h4j:A, 8h4j:B, 8h4j:C, 8h4j:D, 8h4j:E, 8h4j:F, 8h4j:G, 8h4j:H, 7n2w:A, 7n2w:B, 7n2w:C, 7n2w:D
12 4c0w:A 200 58 0.0809 0.1100 0.3793 3.33e-04 4c0x:A, 4c14:A
13 7n2x:A 201 172 0.1544 0.2090 0.2442 0.009 2d5i:A, 1v4b:A, 2z98:A, 2z9b:A, 2z9c:A, 2z9d:A, 2z9d:B
14 1t5b:A 199 117 0.1140 0.1558 0.2650 0.016 1t5b:B
15 3rpe:A 196 77 0.0919 0.1276 0.3247 0.021 3rpe:B
16 2b3d:A 193 48 0.0625 0.0881 0.3542 0.040 2b3d:B
17 2hpv:A 207 111 0.1066 0.1401 0.2613 0.13 2hpv:B, 2hpv:C, 2hpv:D
18 4m0c:A 212 68 0.0551 0.0708 0.2206 0.23 4m0c:B
19 6jxn:B 212 190 0.1801 0.2311 0.2579 0.24 6jxn:A, 6jxn:C, 6jxn:D, 6jxs:A, 6jxs:B, 6jxs:C, 6jxs:D
20 6kd5:B 238 92 0.0882 0.1008 0.2609 0.49
21 6qu0:A 211 144 0.1544 0.1991 0.2917 0.81 6qu0:B
22 5abt:A 246 85 0.0956 0.1057 0.3059 2.1 5a5w:A, 5ab3:A, 5ab3:B, 5ab3:C, 5ahf:A, 5ahi:A, 5g4w:A
23 3ziu:A 621 50 0.0662 0.0290 0.3600 2.6 3ziu:B
24 6xyw:Av 198 52 0.0662 0.0909 0.3462 2.6
25 3hh8:A 280 74 0.0882 0.0857 0.3243 2.9 8yj6:C, 8yj7:B, 8yj7:D, 8yj7:A, 8yj7:C, 8yj8:A, 8yj8:B
26 5hgq:B 482 81 0.0772 0.0436 0.2593 3.2 5hgq:A, 5hgq:D, 5hgq:C
27 3w78:A 210 57 0.0625 0.0810 0.2982 3.8 3w78:B, 3w78:D, 3w78:C, 3w79:A, 3w79:B, 3w79:C, 3w79:D, 3w7a:A, 3w7a:B, 3w7a:C, 3w7a:D
28 7jro:e 94 38 0.0515 0.1489 0.3684 4.3 7jrp:e
29 3w77:A 207 117 0.1140 0.1498 0.2650 7.2 3w77:B
30 3r6w:A 211 55 0.0588 0.0758 0.2909 7.3 3keg:A, 3keg:B, 3lt5:A, 3lt5:B, 4n65:A, 4n65:B, 4n9q:A, 4n9q:B, 3r6w:B, 2v9c:A, 2v9c:B
31 2ef5:A 273 30 0.0441 0.0440 0.4000 8.6 2ef5:B, 2ef5:D, 2ef5:E, 2ef5:F, 2ef5:G
32 7awv:A 210 64 0.0478 0.0619 0.2031 8.8 7awv:B
33 5ejq:A 498 40 0.0515 0.0281 0.3500 9.1
34 3lss:A 438 36 0.0551 0.0342 0.4167 9.1
35 3lss:B 468 36 0.0551 0.0321 0.4167 9.1 6rlt:A, 6rlt:B, 6rlu:A, 6rlu:B, 6rlv:A, 6rlv:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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