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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TYEWSSEEEEPVKKAGPVQVLIVKDDHSFELDETALNRILLSEAVRDKEVVAVSVAGAFRKGKSFLMDFMLRYMYNQESV
DWVGDYNEPLTGFSWRETTGIQIWSEIFLINKPDGKKVAVLLMDTQGTFDSQSTLRDSATVFALSTMISSIQVYNLSQNV
QEDDLQHLQLFTEYGRLAMEETFLKPFQSLIFLVRDWSFPYEFSYGADGGAKFLEKRLKVSGNQHEELQNVRKHIHSCFT
NISCFLLPHPGLKVATNPNFDGKLKEIDDEFIKNLKILIPWLLSPESLDIKEINGNKITCRGLVEYFKAYIKIYQGEELP
HPKSMLQATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAPNDLQTKHLQLKEESVKLFRGVKKMGGEEFSRRYLQQLE
SEIDELYIQYIKHNDSK

The query sequence (length=417) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7ol3:B 425 411 0.9712 0.9529 0.9854 0.0 6b9e:A, 6b9f:A, 6b9f:B, 6b9g:B, 6b9g:C, 6b9g:D, 6b9g:A, 4idn:A, 4idn:B, 4ido:A, 4ido:B, 4idp:A, 4idp:B, 4idp:C, 4idp:D, 4idq:A, 4idq:B, 4idq:C, 4idq:D, 7ol3:A, 3q5d:A, 3q5e:A, 3q5e:C, 3qnu:A, 3qof:A, 3qof:B, 3qof:C, 3qof:D, 6xjn:A
2 6b9e:B 387 406 0.9257 0.9974 0.9507 0.0 6b9d:A, 6b9d:B, 3q5e:E, 3q5e:G
3 5vgr:A 408 410 0.6691 0.6838 0.6805 0.0 5vgr:B, 6xjo:A, 6xjo:B
4 3x1d:A 381 394 0.5300 0.5801 0.5609 4.84e-164
5 7e5a:B 471 378 0.2062 0.1826 0.2275 1.00e-11 7e5a:A
6 8r1a:A 587 392 0.2158 0.1533 0.2296 3.45e-08 2b8w:A, 2b8w:B, 2b92:A, 2b92:B, 2bc9:A, 8cqb:A, 8cqb:B, 2d4h:A, 1f5n:A, 6loj:B, 8r1a:B, 8r1a:C, 8r1a:D, 8r1a:E, 8r1a:F
7 6k1z:A 544 381 0.2038 0.1562 0.2231 4.13e-08
8 6vkj:A 305 318 0.1703 0.2328 0.2233 4.78e-08
9 7ckf:A 256 178 0.1079 0.1758 0.2528 1.49e-05 7ckf:B
10 2d4h:B 284 249 0.1415 0.2077 0.2369 3.21e-05
11 7a62:C 393 112 0.0624 0.0662 0.2321 0.30 7a62:A, 7a62:B, 7a62:D, 8abx:A, 7ah4:A, 7ah4:B, 7ah5:A, 7ah5:B, 7ah6:A, 7ah6:B, 6azu:A, 6azu:B, 6azu:C, 6azu:D, 6azv:A, 6azv:B, 6azv:C, 6azv:D, 6azw:A, 6azw:B, 7b1o:A, 7b1o:B, 6cxu:A, 6cxu:B, 6cxv:A, 6cxv:B, 2d0t:A, 2d0t:B, 2d0u:A, 2d0u:B, 6dpq:A, 6dpq:B, 6dpr:A, 6dpr:B, 7e0o:A, 7e0o:B, 7e0p:A, 7e0p:B, 7e0q:A, 7e0q:B, 7e0s:A, 7e0s:B, 7e0t:A, 7e0t:B, 7e0u:A, 7e0u:B, 6e35:A, 6e35:B, 6e40:A, 6e40:B, 6e40:C, 6e40:D, 6e41:A, 6e41:B, 6e41:C, 6e41:D, 6e42:A, 6e42:B, 6e42:C, 6e42:D, 6e43:A, 6e43:B, 6e43:C, 6e43:D, 6e44:A, 6e44:B, 6e44:C, 6e44:D, 6e45:A, 6e45:B, 6e45:C, 6e45:D, 6e46:A, 6e46:B, 6e46:C, 6e46:D, 5ek2:A, 5ek2:B, 5ek3:A, 5ek3:B, 5ek4:A, 5ek4:B, 5etw:A, 5etw:B, 6f0a:A, 6f0a:C, 8fur:A, 8fur:B, 8fur:C, 8fur:D, 8i7l:A, 8i7l:B, 6kof:A, 6kof:B, 6kps:A, 6kps:B, 6kw7:A, 6kw7:B, 7m63:A, 7m63:B, 7m7d:A, 7m7d:B, 6mq6:A, 6mq6:B, 7nge:A, 7nge:B, 7nge:C, 7nge:D, 6o3i:A, 6o3i:B, 7p0n:A, 7p0n:B, 7p0n:C, 7p0n:D, 7p0r:A, 7p0r:B, 7p0r:C, 7p0r:D, 4pk5:A, 4pk5:B, 4pk6:A, 4pk6:B, 6pu7:A, 6pu7:B, 6pz1:A, 6pz1:B, 6r63:A, 6r63:B, 7rrb:A, 7rrb:B, 7rrc:A, 7rrc:B, 7rrd:A, 7rrd:B, 4u72:A, 4u72:B, 4u74:A, 4u74:B, 6ubp:A, 6ubp:B, 6v52:A, 6v52:B, 5whr:A, 5whr:B, 6wjy:A, 6wjy:B, 5wmu:A, 5wmu:B, 5wmv:A, 5wmv:B, 5wmw:A, 5wmw:B, 5wmx:A, 5wmx:B, 5wn8:A, 5wn8:B, 6wpe:A, 6wpe:B, 6x5y:A, 6x5y:B, 5xe1:A, 5xe1:B, 7yxt:A, 7yxt:B, 7yxt:C, 7yxt:D, 7z2l:A, 7z2l:B, 7z2l:D, 7z2l:C, 7zv3:A, 7zv3:B
12 3r11:B 364 80 0.0600 0.0687 0.3125 0.59 3r0u:A, 3r10:A, 3r11:A, 3r1z:A, 3r1z:B
13 6b9o:B 937 117 0.0743 0.0331 0.2650 2.2 6b9o:A, 6b9p:A, 6b9p:B
14 8bwy:C 4264 120 0.0719 0.0070 0.2500 2.4
15 6zyw:C 4433 120 0.0719 0.0068 0.2500 2.4
16 6epc:R 389 62 0.0384 0.0411 0.2581 7.4 6epd:R, 6epe:R, 6epf:R, 5ln3:R, 5t0h:Y, 5vft:Y
17 6o9l:S 176 85 0.0576 0.1364 0.2824 7.7
18 5swo:B 267 101 0.0528 0.0824 0.2178 9.1 5gji:A, 2iuh:A, 2iui:A, 2iui:B, 7rns:A, 5sxk:B
19 8xxm:3G 84 30 0.0288 0.1429 0.4000 9.8 5k0y:O, 8pj1:o, 8pj2:o, 8pj3:o, 8pj4:o, 8pj5:o, 8pj6:o

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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