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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TWLPLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEA
GVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWN
GRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPG
EPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQP

The query sequence (length=278) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5dqz:B 301 278 0.9892 0.9136 0.9892 0.0 5dlj:D, 5dlj:A, 5dlj:B, 5dlj:C, 5dqt:D, 5dqt:C, 5dqt:A, 5dqt:B, 5dqt:K, 5dqt:L, 5dqt:I, 5dqt:J, 5dqu:A, 5dqu:D, 5dqu:C, 5dqu:B, 5dqz:D, 5dqz:C, 5dqz:A, 5ds4:A, 5ds4:C, 5ds4:D, 5ds4:B, 5ds5:A, 5ds5:C, 5ds5:D, 5ds5:B, 5ds6:A, 5ds6:C, 5ds6:D, 5ds6:B, 3nke:C, 5vvj:A, 5vvj:B, 5vvj:C, 5vvj:D, 5vvk:C, 5vvk:D, 5vvk:A, 5vvk:B, 5vvl:C, 5vvl:D, 5vvl:A, 5vvl:B, 5wfe:A, 5wfe:B, 5wfe:C, 5wfe:D
2 8hi1:A 289 257 0.3849 0.3702 0.4163 5.34e-66 8hi1:C
3 6kdv:B 283 258 0.3849 0.3781 0.4147 1.98e-63 6kdv:D, 6kdv:C, 6kdv:A
4 8fyc:C 310 264 0.3741 0.3355 0.3939 3.67e-61 8fy9:C, 8fy9:F, 8fya:B, 8fya:C, 8fya:F, 8fyb:B, 8fyb:C, 8fyb:E, 8fyb:F, 8fyc:E, 8fyc:B, 8fyd:B, 8fyd:E, 8fyd:F, 8fyd:C
5 8hi1:D 244 266 0.3489 0.3975 0.3647 9.15e-52 8hi1:B
6 8fy9:B 241 262 0.2986 0.3444 0.3168 2.94e-36 8fy9:E, 8fya:E, 8fyc:F
7 8k21:E 295 287 0.2302 0.2169 0.2230 3.02e-15 8k21:d, 8k21:e, 8k21:D, 8k22:E, 8k22:d, 8k22:e, 8k22:D, 8k23:E, 8k23:d, 8k23:e, 8k23:D, 8k24:d, 8k24:e, 8k24:E, 8k24:D, 8k25:d
8 3god:A 320 311 0.2590 0.2250 0.2315 1.37e-10 8flj:A, 8flj:C, 8flj:D, 8flj:B, 3god:B
9 7cr6:C 325 131 0.1439 0.1231 0.3053 4.17e-04 7cr6:B, 7cr6:D, 7cr6:A, 7cr8:J, 7cr8:K, 7cr8:L, 7cr8:I, 7cr8:R, 7cr8:S, 7cr8:T, 7cr8:Q, 7cr8:b, 7cr8:c, 7cr8:d, 7cr8:a, 7cr8:j, 7cr8:k, 7cr8:l, 7cr8:i, 7cr8:r, 7cr8:s, 7cr8:t, 7cr8:q, 7cr8:B, 7cr8:C, 7cr8:D, 7cr8:A
10 8jfk:M 986 68 0.0719 0.0203 0.2941 0.32 8jfk:A, 8jfk:I, 8jfk:E, 8xya:A, 8xyb:A
11 8gl8:A 2290 29 0.0432 0.0052 0.4138 1.2 8gl6:A, 8glj:A, 8glk:A, 8glm:A, 8gln:A
12 6opm:C 359 109 0.0935 0.0724 0.2385 1.3 6opm:A, 6opm:B, 6opm:D
13 7b1s:C 265 98 0.1043 0.1094 0.2959 1.8 7b1s:F, 7b2c:C, 7b2c:F
14 5nxu:A 352 88 0.0935 0.0739 0.2955 3.1 5nxu:B, 5nxu:C
15 7kq3:A 825 88 0.0719 0.0242 0.2273 7.9 7kq3:B, 7kq3:C, 7kq3:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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