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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TVRVGINGFGRIGRNFYRALLAQQEQGTADVEVVAANDITDNSTLAHLLKFDSILGRLPCDVGLEGDDTIVVGRAKIKAL
AVREGPAALPWGDLGVDVVVESTGLFTNAAKAKGHLDAGAKKVIISAPATDEDITIVLGVNDDKYDGSQNIISNASCTTN
CLAPLAKVLDDEFGIVKGLMTTIHAYTQDQNLQDGPHKDLRRARAAALNIVPTSTGAAKAIGLVMPQLKGKLDGYALRVP
IPTGSVTDLTVDLSTRASVDEINAAFKAAAEGRLKGILKYYDAPIVSSDIVTDPHSSIFDSGLTKVIDDQAKVVSWYDNE
WGYSNRLVDLVTLVGKSL

The query sequence (length=338) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8br4:A 339 338 1.0000 0.9971 1.0000 0.0 8br4:B, 8br4:C, 8br4:D, 8br4:E, 8br4:F, 8br4:G, 8br4:H, 8br4:I, 8br4:J, 8br4:K, 8br4:L, 8br4:M, 8br4:N, 8br4:O, 8br4:P
2 8hrq:B 336 339 0.6213 0.6250 0.6195 1.05e-139 8hro:A, 8hro:B, 8hrp:A, 8hrp:B, 8hrp:C, 8hrp:D, 8hrp:E, 8hrp:F, 8hrp:G, 8hrp:H, 8hrq:A, 8hrr:A, 8hrr:B, 8hrs:A, 8hrs:B, 8hrs:C, 8hrs:D, 8hrt:A, 8hrt:B, 8hrt:C, 8hrt:D
3 3cmc:O 334 336 0.5917 0.5988 0.5952 2.26e-138 3cmc:P, 3cmc:Q, 3cmc:R, 1dbv:O, 1dbv:P, 1dbv:Q, 1dbv:R, 2dbv:O, 2dbv:P, 2dbv:Q, 2dbv:R, 3dbv:O, 3dbv:P, 3dbv:Q, 3dbv:R, 4dbv:O, 4dbv:P, 4dbv:Q, 4dbv:R, 1gd1:O, 1gd1:P, 1gd1:Q, 1gd1:R, 1npt:O, 1npt:P, 1npt:Q, 1npt:R, 1nq5:O, 1nq5:Q, 1nq5:A, 1nq5:C, 1nqa:O, 1nqa:P, 1nqa:Q, 1nqa:R, 1nqo:O, 1nqo:Q, 1nqo:A, 1nqo:C
4 2ep7:B 339 344 0.5858 0.5841 0.5756 1.97e-134 2ep7:A
5 1hdg:O 332 335 0.5769 0.5873 0.5821 5.16e-134 1hdg:Q
6 1cer:O 331 334 0.5947 0.6073 0.6018 2.68e-132 1cer:P, 1cer:Q, 1cer:R, 1cer:A, 1cer:B, 1cer:C, 1cer:D, 2g82:O, 2g82:P, 2g82:Q, 2g82:R, 2g82:A, 2g82:B, 2g82:C, 2g82:D, 1vc2:A
7 3doc:A 335 336 0.5651 0.5701 0.5685 9.96e-128 3doc:B, 3doc:C, 3doc:D
8 3l0d:A 332 339 0.5325 0.5422 0.5310 1.16e-121 3l0d:B
9 3gnq:C 335 330 0.5414 0.5463 0.5545 2.87e-120 3gnq:B, 3gnq:D, 3gnq:E, 3gnq:F, 3gnq:G, 3gnq:H
10 3hja:A 334 337 0.5651 0.5719 0.5668 2.90e-120 3hja:B, 3hja:C, 3hja:D
11 1nbo:O 337 334 0.5414 0.5430 0.5479 1.60e-116 1jn0:O, 1jn0:A, 1jn0:B, 1nbo:A, 1nbo:B, 2pkq:P, 2pkq:R, 2pkq:S, 2pkr:O, 2pkr:R, 2pkr:P, 2pkr:Q, 2pkr:A, 2pkr:B, 2pkr:C, 2pkr:D, 2pkr:H, 2pkr:I, 2pkr:L, 2pkr:M, 7q53:P, 7q53:R, 7q54:R, 7q54:P, 7q54:B, 7q54:D, 7q55:P, 7q55:R, 7q55:B, 7q55:D, 7q55:F, 7q55:H, 7q55:J, 7q55:L, 7q56:J, 7q56:L, 7q56:B, 7q56:D, 7q56:R, 7q56:P, 7q56:H, 7q56:F, 7q57:P, 7q57:R, 7q57:B, 7q57:D, 7q57:H, 7q57:F, 7q57:J, 7q57:L, 7q57:N, 7q57:T, 1rm3:O, 1rm3:A, 1rm3:B, 1rm4:O, 1rm4:A, 1rm4:B, 1rm5:O, 1rm5:A, 1rm5:B
12 1obf:O 335 331 0.5207 0.5254 0.5317 2.99e-113 1obf:P
13 5vmt:B 334 334 0.5355 0.5419 0.5419 8.88e-113 5vmt:A, 5vmt:C, 5vmt:D, 5vmt:F, 5vmt:G, 5vmt:H
14 8de5:A 338 338 0.5178 0.5178 0.5178 2.17e-112
15 1ywg:O 337 334 0.5237 0.5252 0.5299 1.36e-111 2b4r:O, 2b4r:P, 2b4r:Q, 2b4r:R, 2b4t:O, 2b4t:P, 2b4t:Q, 2b4t:R, 1ywg:P, 1ywg:Q, 1ywg:R
16 4mvj:B 332 338 0.5148 0.5241 0.5148 4.34e-111 1dc4:A, 1dc4:B, 1dc6:A, 1dc6:B, 1gad:O, 1gad:P, 1gae:O, 1gae:P, 6io6:A, 4mvj:A, 4mvj:C, 4mvj:D, 4mvj:E, 4mvj:F, 4mvj:G, 4mvj:I, 4mvj:J, 4mvj:K, 4mvj:L, 4mvj:M, 4mvj:O, 4mvj:P, 6utm:A, 6utm:B, 6utn:A, 6utn:B, 6uto:A, 6uto:B, 2vyn:A, 2vyn:B, 2vyn:C, 2vyv:A, 2vyv:B, 2vyv:C, 5za0:A
17 3b1j:A 338 339 0.5355 0.5355 0.5339 5.71e-111 3b1j:B, 3b1k:A, 3b1k:H, 3b1k:B, 3b1k:G, 3b20:A, 3b20:B, 3b20:O, 3b20:P, 3b20:Q, 3b20:R, 2d2i:A, 2d2i:B, 2d2i:O, 2d2i:P, 2d2i:Q, 2d2i:R, 2duu:A, 2duu:B, 2duu:O, 2duu:P, 2duu:Q, 2duu:R
18 4p8r:A 331 337 0.5296 0.5408 0.5312 5.76e-111 4p8r:B, 4p8r:C, 4p8r:D
19 6fzi:B 332 342 0.5562 0.5663 0.5497 1.42e-110 6fzi:A, 6fzi:C, 6fzi:D
20 7jwk:C 333 341 0.5118 0.5195 0.5073 1.71e-110 7jwk:A, 7jwk:B, 7jwk:D
21 6ghr:B 342 330 0.5148 0.5088 0.5273 5.11e-110 4boy:A, 4boy:B, 6gfo:A, 6gfo:B, 6gfo:C, 6gfo:D, 6gfp:A, 6gfp:B, 6gfq:B, 6gfq:A, 6gfr:A, 6gfr:B, 6gg7:B, 6gg7:A, 6ghl:A, 6ghl:D, 6ghl:B, 6ghl:C, 6ghr:D, 6ghr:A, 6ghr:C, 6gve:D, 6gve:A, 6gve:E, 6gve:F, 6gve:I, 6gve:K, 6gve:N, 6gve:O, 3zcx:A, 3zcx:B, 3zdf:B, 3zdf:A
22 6m5x:O 334 337 0.5207 0.5269 0.5223 7.54e-110 6m5x:R, 6m5x:P, 6m5x:Q
23 7xzg:A 334 339 0.5237 0.5299 0.5221 2.38e-108 7xzg:B, 7xzg:C, 7xzg:D
24 3e5r:O 336 340 0.4911 0.4940 0.4882 4.20e-108 3e5r:A, 3e5r:B, 3e5r:C, 3v1y:O, 3v1y:A, 3v1y:B, 3v1y:C
25 5m6d:A 346 341 0.5266 0.5145 0.5220 1.04e-107 6fzh:A, 6fzh:B, 6ite:P, 6ite:Q, 6ite:R, 6ite:O
26 3pym:A 332 339 0.5207 0.5301 0.5192 1.32e-107 3pym:B
27 7q54:C 368 337 0.5473 0.5027 0.5490 2.27e-107 2pkq:O, 2pkq:Q, 2pkq:T, 7q53:O, 7q53:Q, 7q54:Q, 7q54:O, 7q54:A, 7q55:O, 7q55:Q, 7q55:A, 7q55:C, 7q55:E, 7q55:G, 7q55:I, 7q55:K, 7q56:K, 7q56:E, 7q56:I, 7q56:A, 7q56:G, 7q56:C, 7q56:Q, 7q56:O, 7q57:O, 7q57:Q, 7q57:A, 7q57:C, 7q57:G, 7q57:E, 7q57:I, 7q57:K, 7q57:M, 7q57:S
28 6qun:O 334 340 0.4970 0.5030 0.4941 3.05e-107 6qun:R, 6quq:O, 6quq:R, 4z0h:O, 4z0h:R
29 7zq3:R 348 337 0.5414 0.5259 0.5430 3.84e-107 7zq3:O, 7zq4:O, 7zq4:R, 7zqk:O, 7zqk:R
30 7bew:A 330 335 0.5148 0.5273 0.5194 6.89e-107 7bex:A
31 5utm:A 345 342 0.5266 0.5159 0.5205 2.29e-106 5jy6:A, 5jy6:B, 5jy6:C, 5jy6:D, 5jya:A, 5jya:B, 5jya:C, 5jya:D, 5jye:A, 5jye:C, 4qx6:A, 4qx6:B, 4qx6:C, 4qx6:D, 5utl:A, 5utl:B, 5utl:C, 5utl:D, 5utm:B, 5utm:C, 5utm:D, 5v8x:A, 5v8x:B, 5v8x:C, 5v8x:D, 5y37:A, 5y37:B
32 3k2b:A 337 337 0.5325 0.5341 0.5341 5.06e-106 3k2b:B, 3k2b:C, 3k2b:D, 3k2b:E, 3k2b:F, 3k2b:G, 3k2b:H, 3k2b:O, 3k2b:Q, 6kez:A, 6kez:B, 6kez:C, 6kez:D, 6kez:E, 6kez:F, 6kez:G, 6kez:H, 3qv1:A, 3qv1:D, 3qv1:B, 3qv1:C, 3qv1:F, 3qv1:E, 3rvd:A, 3rvd:D, 3rvd:B, 3rvd:C, 3rvd:O, 3rvd:Q, 3rvd:F, 3rvd:G, 3rvd:E, 3rvd:H
33 1a7k:A 358 346 0.5118 0.4832 0.5000 8.89e-106 1a7k:B, 1a7k:C, 1a7k:D, 1gyp:A, 1gyp:B, 1gyp:C, 1gyp:D, 1gyq:A, 1gyq:B, 1gyq:C, 1gyq:D, 1i32:A, 1i32:B, 1i32:C, 1i32:D, 1i32:E, 1i32:F, 1i33:A, 1i33:B, 1i33:C, 1i33:D, 1i33:E, 1i33:F
34 8oha:B 336 338 0.5178 0.5208 0.5178 1.32e-105 8oha:A, 8oha:C, 8oha:D, 8oha:E, 8oha:F, 8oha:G, 8oha:H
35 4k9d:A 338 338 0.5148 0.5148 0.5148 1.73e-105 4k9d:B, 4k9d:C, 4k9d:D, 4k9d:E, 4k9d:F, 4k9d:G, 4k9d:H
36 3dmt:A 359 346 0.5030 0.4735 0.4913 3.07e-105 3dmt:B, 3dmt:C, 3dmt:D, 3ids:D, 1k3t:C, 1ml3:B, 1ml3:C, 1ml3:D, 1qxs:C, 1qxs:D, 1qxs:A, 1qxs:B, 2x0n:A, 2x0n:B, 2x0n:O, 2x0n:P, 2x0n:Q, 2x0n:R
37 3lvf:P 338 334 0.5089 0.5089 0.5150 6.75e-105 3hq4:R, 3hq4:O, 3hq4:P, 3hq4:Q, 3k73:Q, 3k73:O, 3k73:P, 3k73:R, 3k9q:Q, 3k9q:O, 3k9q:P, 3k9q:R, 3ksd:Q, 3ksd:R, 3ksd:O, 3ksd:P, 3ksz:O, 3ksz:P, 3ksz:R, 3ksz:Q, 3kv3:O, 3kv3:Q, 3kv3:R, 3kv3:P, 3l4s:Q, 3l4s:P, 3l4s:O, 3l4s:R, 3l6o:Q, 3l6o:P, 3l6o:R, 3l6o:O, 3lc1:P, 3lc1:R, 3lc1:O, 3lc1:Q, 3lc2:O, 3lc2:Q, 3lc2:R, 3lc2:P, 3lvf:R, 3lvf:O, 3lvf:Q, 5t73:A, 5t73:B, 5t73:C, 5t73:D, 3vaz:P, 3vaz:R, 3vaz:O, 3vaz:Q, 3vaz:B, 3vaz:A
38 6nlx:C 335 339 0.5059 0.5104 0.5044 6.28e-104 6nlx:B, 6nlx:D, 5ur0:A, 5ur0:B, 5ur0:C, 5ur0:D
39 6m61:O 336 333 0.5000 0.5030 0.5075 4.00e-103 6ade:A, 5ddi:P, 5ddi:R, 5ddi:S, 6iq6:A, 6iq6:B, 6iq6:C, 6iq6:D, 6iq6:E, 1j0x:P, 1j0x:R, 6lgj:A, 6lgj:B, 6lgj:C, 6lgj:D, 6lgk:A, 6lgk:B, 6lgk:C, 6lgm:A, 6lgm:B, 6lgm:C, 6m61:Q, 6m61:P, 4o59:O, 4o59:P, 4o59:R, 4o59:Q, 4o63:P, 4o63:Q, 4o63:R, 8p5f:AAA, 8p5f:DDD, 8p5f:EEE, 8p5f:GGG, 5tso:P, 5tso:R, 5tso:S, 7u5m:A, 7u5m:B, 7u5m:C, 7u5m:D, 1u8f:P, 1u8f:Q, 1u8f:R, 4wnc:O, 4wnc:E, 4wnc:A, 4wnc:B, 4wnc:C, 4wnc:D, 4wni:O, 4wni:A, 4wni:B, 1znq:O, 1znq:P, 1znq:R, 1znq:Q
40 4lsm:A 331 336 0.4882 0.4985 0.4911 1.05e-102 4lsm:B
41 3cif:A 338 340 0.5030 0.5030 0.5000 1.72e-102 3cif:B, 3cif:C, 3cif:D, 3cps:A, 3cps:B, 8pvf:A, 1vsv:A, 1vsv:B, 1vsv:C, 1vsv:D
42 6ok4:A 334 338 0.5000 0.5060 0.5000 6.07e-102 6ok4:B, 6ok4:C, 6ok4:D, 6wyc:A, 6wyc:B, 6wyc:C, 6wyc:D, 6x2e:A, 6x2e:C, 6x2e:D
43 5ld5:C 342 346 0.5266 0.5205 0.5145 3.27e-101 5ld5:A, 5ld5:B, 5ld5:D
44 3sth:C 340 334 0.5059 0.5029 0.5120 7.08e-101 3sth:A, 3sth:B, 3sth:D
45 2vyn:D 334 334 0.4852 0.4910 0.4910 2.33e-99 2vyv:D
46 6px2:A 332 334 0.5030 0.5120 0.5090 4.43e-99 6px2:B, 6px2:C, 6px2:D, 6px2:E, 6px2:F, 6px2:G, 6px2:H
47 1dss:G 333 340 0.5030 0.5105 0.5000 8.88e-99 1dss:R, 1gpd:G, 1gpd:R, 1ihx:A, 1ihx:B, 1ihx:C, 1ihx:D, 1ihy:A, 1ihy:B, 1ihy:C, 1ihy:D, 1szj:G, 1szj:R
48 7c5o:O 338 331 0.5000 0.5000 0.5106 1.80e-98 7c5f:O, 7c5f:P, 7c5f:Q, 7c5f:R, 7c5g:O, 7c5g:P, 7c5g:Q, 7c5g:R, 7c5h:O, 7c5h:P, 7c5h:Q, 7c5h:R, 7c5i:O, 7c5i:P, 7c5i:Q, 7c5i:R, 7c5j:O, 7c5j:P, 7c5j:Q, 7c5j:R, 7c5k:O, 7c5k:P, 7c5k:Q, 7c5k:R, 7c5l:O, 7c5l:P, 7c5l:Q, 7c5l:R, 7c5m:O, 7c5m:P, 7c5m:Q, 7c5m:R, 7c5n:O, 7c5n:P, 7c5n:Q, 7c5n:R, 7c5o:P, 7c5o:Q, 7c5o:R, 7c5p:O, 7c5p:P, 7c5p:Q, 7c5p:R, 7c5q:O, 7c5q:P, 7c5q:Q, 7c5q:R, 7c5r:O, 7c5r:P, 7c5r:Q, 7c5r:R, 7c7k:O, 7c7k:P, 7c7k:Q, 7c7k:R
49 3h9e:P 337 332 0.4852 0.4866 0.4940 6.21e-98 5c7o:O, 5c7o:P, 3h9e:O, 3pfw:O, 3pfw:P
50 8hmn:D 340 335 0.4882 0.4853 0.4925 7.15e-96 8hmn:A, 8hmn:B, 8hmn:C, 6iqm:A, 6iqm:B, 6iqm:C, 6iqm:D
51 3gpd:R 334 333 0.4852 0.4910 0.4925 1.95e-95 3gpd:G
52 7www:A 336 334 0.4941 0.4970 0.5000 9.42e-95
53 9iil:A 341 335 0.4497 0.4457 0.4537 5.69e-94 9iil:B, 9iil:C, 9iil:D, 9iim:A, 9iim:C, 9iim:B, 9iim:D, 9ij6:A, 9ij6:C, 9ij6:B, 9ij6:D, 8zn1:A, 8zn1:C, 8zn1:B, 8zn1:D, 8zn4:A, 8zn4:B, 8zn4:C, 8zn4:D, 8zoz:A, 8zoz:C, 8zoz:B, 8zoz:D
54 2i5p:O 309 335 0.4615 0.5049 0.4657 8.86e-94 2i5p:P
55 5vmt:E 293 329 0.4704 0.5427 0.4833 4.48e-89
56 2xf8:M 327 331 0.4172 0.4312 0.4260 2.13e-84 2xf8:A, 2xf8:C, 2xf8:E, 2xf8:G, 2xf8:I, 2xf8:K, 2xf8:O
57 8jb1:A 468 332 0.3462 0.2500 0.3524 4.21e-56 8jb1:B
58 3kv6:D 448 103 0.0947 0.0714 0.3107 4.25e-04 3kv5:D, 3kv5:A, 3kv6:A, 3kv9:A, 3kva:A, 3u78:A
59 8f8y:B 433 150 0.1154 0.0901 0.2600 0.008 8f8y:A, 8f8z:A, 8f8z:B, 3kqi:A, 7m10:A, 3pu3:A, 3pu3:B, 3pu8:B, 3pu8:A, 3pua:A, 3pus:A, 3pus:B
60 3tz6:A 342 97 0.0799 0.0789 0.2784 0.025 3vos:A
61 7uv9:K 407 103 0.0710 0.0590 0.2330 0.18 4qwn:A, 4qwn:C, 4qx7:A, 4qx7:C, 4qx8:A, 4qx8:C, 4qxb:A, 4qxb:C, 4qxc:A, 4qxc:C, 4qxh:A, 4qxh:C, 4tn7:A, 4tn7:C, 7uva:A, 7uva:D, 2yu1:A, 2yu2:A
62 8rq9:A 316 65 0.0651 0.0696 0.3385 0.40 8rq1:A, 8rq8:A, 8rq9:C, 8rqa:A, 8rqc:A, 8rqc:D
63 1ys4:A 348 89 0.0680 0.0661 0.2584 1.3 1ys4:B
64 2y9h:M 193 76 0.0503 0.0881 0.2237 1.3 2y9h:K, 2y9h:O
65 3kv4:A 432 100 0.0769 0.0602 0.2600 1.9 4do0:A, 3k3n:A, 3k3o:A, 2wwu:A
66 2d1r:A 539 41 0.0503 0.0315 0.4146 3.2 2d1q:A, 2d1s:A, 2d1t:A
67 6ueh:A 484 87 0.0710 0.0496 0.2759 5.6
68 7q1c:A 427 86 0.0828 0.0656 0.3256 5.8 7q1b:A, 7q1c:B
69 3gvp:A 433 46 0.0503 0.0393 0.3696 7.8 3gvp:B, 3gvp:C, 3gvp:D, 3mtg:A, 3mtg:B
70 3ce6:A 486 125 0.1065 0.0741 0.2880 8.4 3ce6:B, 3ce6:C, 3ce6:D, 3dhy:A, 3dhy:B, 3dhy:C, 3dhy:D, 2ziz:A, 2ziz:B, 2ziz:C, 2ziz:D, 2zj0:A, 2zj0:B, 2zj0:C, 2zj0:D, 2zj1:A, 2zj1:B, 2zj1:C, 2zj1:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218