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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
TMKVIDPQHSDKPNVLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNFALKKKGN
VTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNS
LEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMF
EKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSK
RGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAKNFDKMAQIPNFQKNLLFEENNFKPFKYNDLGALAYL
GSERAIATIRSGKRTFYTGGGLMTFYLWRILYLSMILSARSRLKVFFDWIKLAFFKRDFFKGL

The query sequence (length=463) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4g6h:A 472 472 1.0000 0.9809 0.9809 0.0 4g6g:A, 4g6g:B, 4g6h:B, 4g73:A, 4g73:B, 4g74:A, 4g74:B, 4g9k:A, 4g9k:B, 4gap:A, 4gap:B, 4gav:A, 4gav:B
2 5yjy:B 465 468 0.9633 0.9591 0.9530 0.0 5yjw:A, 5yjx:A, 5yjx:B, 5yjy:A
3 5jwa:A 495 339 0.2613 0.2444 0.3569 3.24e-55 5jwa:H, 5jwb:A, 5jwb:H, 5jwc:A, 5jwc:H
4 5na1:A 398 417 0.2527 0.2940 0.2806 1.12e-34 5na4:A
5 6bdo:D 395 446 0.2549 0.2987 0.2646 4.88e-31 6bdo:B, 6bdo:A, 6bdo:C, 5kmp:A, 5kmp:B, 5kmq:A, 5kmq:B, 5kmq:C, 5kmq:D, 5kmr:B, 5kmr:A, 5kmr:C, 5kmr:D, 5kms:A, 5kms:B, 5kms:C, 5kms:D, 4nwz:A, 4nwz:B, 4nwz:C, 4nwz:D, 5wed:B, 5wed:A, 5wed:C, 5wed:D
6 3dh9:A 482 246 0.1361 0.1307 0.2561 3.69e-05 3dgh:A, 3dgh:B, 3dh9:B, 2nvk:X
7 7xpi:A 363 253 0.1404 0.1791 0.2569 5.25e-05 7ytl:A
8 3hyv:A 429 99 0.0691 0.0746 0.3232 1.08e-04 3hyv:B, 3hyv:C, 3hyv:D, 3hyv:E, 3hyv:F, 3hyw:A, 3hyw:B, 3hyw:C, 3hyw:D, 3hyw:E, 3hyw:F, 3hyx:A, 3hyx:B, 3hyx:C, 3hyx:D, 3hyx:E, 3hyx:F
9 3oc4:A 422 168 0.0994 0.1090 0.2738 0.001 3oc4:B
10 3ict:A 557 259 0.1188 0.0987 0.2124 0.002 3icr:A, 3icr:B, 3ics:A, 3ics:B, 3ict:B
11 3lxd:A 409 264 0.1382 0.1565 0.2424 0.002
12 3t2z:A 427 286 0.1296 0.1405 0.2098 0.004 3kpk:A, 3sx6:A, 3sxi:A, 3sy4:A, 3syi:A, 3sz0:A, 3szc:A, 3szf:A, 3szw:A, 3t0k:A, 3t14:A, 3t2k:A, 3t2y:A, 3t2z:B, 3t31:A
13 1f8w:A 447 146 0.0907 0.0940 0.2877 0.004 1joa:A, 1nhp:A, 1nhq:A, 1nhr:A, 1nhs:A, 1npx:A, 2npx:A
14 1lvl:A 458 189 0.1080 0.1092 0.2646 0.004
15 3h8i:A 356 156 0.0886 0.1152 0.2628 0.004 3h8i:B, 3h8l:A, 3h8l:B
16 8a56:B 539 259 0.1274 0.1095 0.2278 0.005 8a56:A
17 6pfz:A 541 313 0.1404 0.1201 0.2077 0.008 6pfz:D, 6pfz:C, 6pfz:B
18 1hyu:A 521 153 0.0972 0.0864 0.2941 0.015 1fl2:A, 4o5q:A, 4o5u:A, 4xvg:A, 4ykf:A, 4ykg:A
19 8wik:A 364 145 0.0929 0.1181 0.2966 0.022 8jsc:C
20 2r9z:B 453 153 0.0799 0.0817 0.2418 0.023 2r9z:A, 2rab:A, 2rab:B
21 3nt6:A 565 264 0.1382 0.1133 0.2424 0.027 3nt6:B, 3nta:A, 3nta:B, 3ntd:A, 3ntd:B, 4ocg:A, 4ocg:B
22 7mgo:A 489 242 0.1274 0.1207 0.2438 0.033
23 3lad:A 472 137 0.0778 0.0763 0.2628 0.036 3lad:B
24 2c3c:A 522 302 0.1425 0.1264 0.2185 0.045 2c3c:B, 2c3d:A, 2c3d:B, 7mgn:A, 7mgn:B, 7mgo:B, 1mo9:A, 1mo9:B, 1mok:A, 1mok:B, 1mok:C, 1mok:D, 3q6j:A, 3q6j:B
25 1ger:B 449 240 0.1469 0.1514 0.2833 0.063 1ger:A, 1ges:A, 1ges:B, 1get:A, 1get:B, 1geu:A, 1geu:B
26 6awa:A 475 120 0.0734 0.0716 0.2833 0.069 6awa:B, 5tr3:A, 5tr3:B
27 2v3a:A 381 256 0.1382 0.1680 0.2500 0.10 2v3b:A
28 2cdu:A 451 271 0.1361 0.1397 0.2325 0.11 2cdu:B
29 8k40:A 448 244 0.1296 0.1339 0.2459 0.11 8k40:B, 8k41:A
30 6ruz:A 443 269 0.1231 0.1287 0.2119 0.41 6ruz:B, 6ruz:C, 6ruz:D, 6rvb:A, 6rvb:B, 6rvb:C, 6rvb:D, 6rvh:A, 6rvh:B, 6rvh:C, 6rvh:D
31 2hqm:A 461 116 0.0734 0.0738 0.2931 0.41 2hqm:B
32 1xhc:A 346 410 0.1857 0.2486 0.2098 0.62
33 3ven:A 571 52 0.0346 0.0280 0.3077 0.68 3veo:A, 3ver:A, 3ves:A, 3vet:A, 3vew:A, 3vex:A, 3vez:A, 3vf2:A, 3vf4:A
34 5er0:A 450 283 0.1361 0.1400 0.2226 0.84 5er0:B, 5er0:C, 5er0:D, 5vn0:A, 5vn0:B, 5vn0:C, 5vn0:D, 5vn0:E, 5vn0:F, 5vn0:G, 5vn0:H, 5voh:A, 5voh:B, 5voh:C, 5voh:D
35 8pxk:A 403 212 0.1080 0.1241 0.2358 1.1 1d7y:A, 1f3p:A, 2gqw:A, 2gr0:A, 2gr1:A, 2gr2:A, 2gr3:A, 4h4p:A, 4h4q:A, 4h4r:A, 4h4s:A, 4h4t:A, 4h4u:A, 4h4v:A, 4h4w:A, 4h4x:A, 4h4y:A, 4h4z:A, 4h50:A, 8pxl:A, 2yvf:A, 2yvg:A, 2yvj:A, 2yvj:P
36 1ebd:A 455 176 0.0929 0.0945 0.2443 1.1 1ebd:B
37 3cgb:A 444 80 0.0497 0.0518 0.2875 1.5 3cgb:B, 3cgc:A, 3cgc:B, 3cgd:A, 3cgd:B, 3cge:A, 3cge:B
38 6brd:A 474 21 0.0259 0.0253 0.5714 2.2 6brd:B, 6brd:C, 5vqb:A, 5vqb:B, 5vqb:C
39 5wvp:A 924 85 0.0540 0.0271 0.2941 2.3
40 4ylf:B 468 115 0.0756 0.0748 0.3043 2.5 4ylf:D, 4yry:B, 4yry:D
41 6mo6:B 414 113 0.0540 0.0604 0.2212 2.7 8dhk:A, 8dhk:B, 6mo6:A, 6mo6:C, 6mo6:D, 6mp5:A, 6mp5:B, 6mp5:C, 6mp5:D, 6oi5:A, 6oi5:B, 6oi6:A, 6oi6:B, 6oib:A, 6oib:B, 6oic:A, 6oic:B, 6wh6:A, 6wh6:B
42 7d5s:RD 265 70 0.0540 0.0943 0.3571 3.1 6lqu:RD, 7suk:NJ, 5wlc:NJ
43 4fx9:B 443 39 0.0346 0.0361 0.4103 4.8 4fx9:A, 5l1n:A, 5l1n:B
44 2gmh:A 581 64 0.0389 0.0310 0.2812 4.9 2gmh:B, 2gmj:A, 2gmj:B
45 3fkq:A 354 117 0.0713 0.0932 0.2821 5.9
46 5kow:A 474 21 0.0216 0.0211 0.4762 5.9 6c7s:A, 5kox:A
47 6ihd:B 304 212 0.1080 0.1645 0.2358 6.1 6ihd:A, 6ihe:A, 6ihe:B
48 2bc0:A 473 140 0.0907 0.0888 0.3000 7.6 2bc0:B, 2bc1:A, 2bc1:B, 2bcp:A, 2bcp:B
49 2nzy:C 351 32 0.0302 0.0399 0.4375 9.6 2nzx:A, 2nzx:B, 2nzx:C, 2nzy:A, 2nzy:B, 5zoi:A, 5zoi:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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